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Uncovering novel roles of the CARD11-BCL10-MALT1 (CBM) complex in immunity: unique insights from human primary immunodeficiency diseases

Uncovering novel roles of the CARD11-BCL10-MALT1 (CBM) complex in immunity: unique insights from human primary immunodeficiency diseases
揭示 CARD11-BCL10-MALT1 (CBM) 复合物在免疫中的新作用：来自人类原发性免疫缺陷疾病的独特见解
批准号：
417270
负责人：
Lu Yi-Chin
金额：
$7.65万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-11-01 至 2022-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=417270&lang=en
关键词：
Antigen Receptor Signalling Cbm Complex Nf-Kb Regulation Primary Immunodeficiency Diseases Severe Combined Immunodeficiency Toll-Like Receptor Signalling

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中文摘要
翻译
原发性免疫缺陷疾病（PIDs）是一组罕见的遗传性疾病，其中免疫系统在出生时被破坏或缺失。由于免疫系统是我们抵御细菌和病毒等细菌的主要屏障，因此感染的病人
英文摘要
Primary immunodeficiency diseases (PIDs) are a group of rare genetic disorders in which the immune system is broken or missing at birth. Since the immune system is our primary defense against germs such as bacteria and viruses, this leaves affected patien
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