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The role of mitophagy and extracellular matrix (ECM) stiffness in the regulation of epithelial-to-mesenchymal transition (EMT), and subsequent metastasis in non-small cell lung cancer (NSCLC) model.

The role of mitophagy and extracellular matrix (ECM) stiffness in the regulation of epithelial-to-mesenchymal transition (EMT), and subsequent metastasis in non-small cell lung cancer (NSCLC) model.
线粒体自噬和细胞外基质 (ECM) 硬度在非小细胞肺癌 (NSCLC) 模型中上皮间质转化 (EMT) 和随后转移的调节中的作用。
批准号：
415961
负责人：
Alizadeh Javad
金额：
$10.93万
依托单位：
University of Manitoba
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-11-01 至 2022-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=415961&lang=en
关键词：
Bcl2 Like Protein 13 (Bcl2l13), Extracellular Matrix (Ecm) Crispr Gene Editing, Orthotopic Mouse Model, 3d Bioprinting In Vivo Imaging System (Ivis) Lung Cancer, Epithelial-Mesenchymal Transition (Emt) Metastasis, Selective Autophagy, Mitophagy Non-S

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相关文献

中文摘要
翻译
肺癌是加拿大癌症相关死亡的主要原因。肺癌死亡的一个主要风险是癌细胞逃离肺部侵入其他器官，导致新的癌症在全身出现。这个过程被称为“转移”
英文摘要
Lung cancer is the main cause of cancer-related deaths in Canada. A major risk for lung cancer deaths is when cancer cells escape the lung to invade other organs, causing new cancers to show up throughout the body. This process is called 'metastasis' and
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