Impact of disease-induced dysbiotic microbiota on the protective functions of innate T cells during type 1 diabetes
Impact of disease-induced dysbiotic microbiota on the protective functions of innate T cells during type 1 diabetes
批准号:
428925
负责人:
Kuypers Meggie
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-12-01 至 2020-12-01
中文摘要
1型糖尿病(T1D)是一种自身免疫性疾病,其特征是免疫反应异常,攻击胰腺中产生胰岛素的细胞。除了遗传易感性外,肠道微生物群组成的改变(称为生态失调)也可能导致疾病
英文摘要
"Type I diabetes (T1D) is an autoimmune disease characterized by abnormal immune responses that attack insulin-producing cells in the pancreas. In addition to genetic susceptibility, alterations in intestinal microbiota composition - called dysbiosis - ha
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