A comprehensive investigation of the CRISPR-Cas9 / anti-CRISPR evolutionary arms race in Enterococcus faecalis: in vitro mechanism and in vivo implications
A comprehensive investigation of the CRISPR-Cas9 / anti-CRISPR evolutionary arms race in Enterococcus faecalis: in vitro mechanism and in vivo implications
批准号:
452650
负责人:
Maxwell Karen L
金额:
$68.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01
中文摘要
和人类一样,细菌也会被病毒感染和杀死,它们已经形成了一种免疫系统来帮助保护自己。这种细菌免疫系统,被称为CRISPR-Cas,不仅可以防止病毒感染,而且在血液中也起着重要作用
英文摘要
Like people, bacteria can be infected and killed by viruses, and they have developed an immune system to help protect them. This bacterial immune system, known as CRISPR-Cas, not only protects against virus infection, but it also plays important roles in
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会议论文
Investigation of phage-derived contributions to bacterial fitness and virulence
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批准号:402195
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项目类别:Operating Grants
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资助金额:$71.06万
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财政年份:2019
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负责人:Maxwell Karen L
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依托单位:
Protein inhibitors of CRISPR-Cas9 mediated genome editing: discovery, characterization and development for novel biotechnological applications
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批准号:355734
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项目类别:Operating Grants
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资助金额:$60.08万
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财政年份:2016
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负责人:Maxwell Karen L
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依托单位:
海外基金