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A comprehensive investigation of the CRISPR-Cas9 / anti-CRISPR evolutionary arms race in Enterococcus faecalis: in vitro mechanism and in vivo implications

A comprehensive investigation of the CRISPR-Cas9 / anti-CRISPR evolutionary arms race in Enterococcus faecalis: in vitro mechanism and in vivo implications
粪肠球菌 CRISPR-Cas9/抗 CRISPR 进化军备竞赛的全面研究:体外机制和体内影响
批准号:
452650
负责人:
Maxwell Karen L
金额:
$68.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01

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中文摘要
翻译
和人类一样,细菌也会被病毒感染和杀死,它们已经形成了一种免疫系统来帮助保护自己。这种细菌免疫系统,被称为CRISPR-Cas,不仅可以防止病毒感染,而且在血液中也起着重要作用
英文摘要
Like people, bacteria can be infected and killed by viruses, and they have developed an immune system to help protect them. This bacterial immune system, known as CRISPR-Cas, not only protects against virus infection, but it also plays important roles in
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Investigation of phage-derived contributions to bacterial fitness and virulence
  • 批准号:
    402195
  • 项目类别:
    Operating Grants
  • 资助金额:
    $71.06万
  • 财政年份:
    2019
  • 负责人:
    Maxwell Karen L
  • 依托单位:
Protein inhibitors of CRISPR-Cas9 mediated genome editing: discovery, characterization and development for novel biotechnological applications
  • 批准号:
    355734
  • 项目类别:
    Operating Grants
  • 资助金额:
    $60.08万
  • 财政年份:
    2016
  • 负责人:
    Maxwell Karen L
  • 依托单位:
海外基金