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Novel high throughput functional approach to investigate the cellular basis of sex-dependent differences in chemotherapy-induced peripheral neuropathy (CIPN) in primary dorsal root ganglia (DRG) and using cannabidiol (CBD) as a potential molecular treatme

Novel high throughput functional approach to investigate the cellular basis of sex-dependent differences in chemotherapy-induced peripheral neuropathy (CIPN) in primary dorsal root ganglia (DRG) and using cannabidiol (CBD) as a potential molecular treatme
新颖的高通量功能方法研究初级背根神经节（DRG）化疗引起的周围神经病变（CIPN）性别依赖性差异的细胞基础，并使用大麻二酚（CBD）作为潜在的分子治疗
批准号：
453928
负责人：
Ghovanloo Mohammad-Reza
金额：
$10.2万
依托单位：
Yale University (Connecticut)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-09-01 至 2023-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=453928&lang=en
关键词：
Cannabidiol Chemotherapy Induced Peripheral Neuropathy Electrophysiology Excitability Ion Channel Neuropathy Pain Patch-Clamp Sex-Dependence Sodium Channel

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中文摘要
翻译
慢性疼痛是许多疾病的特征，包括化疗引起的周围神经病变(CIPN)。目前还没有有效的治疗慢性疼痛的方法，而且许多方法非常容易上瘾。因此，疼痛仍然是一种未得到满足的医疗需求。热情的
英文摘要
Chronic pain is a defining feature of many conditions, including chemotherapy-induced peripheral neuropathy (CIPN). There are currently no effective treatments for chronic pain, and many are highly addictive. Thus, pain remains an unmet medical need. Epid
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