Characterizing the nucleotide-binding domain leucine-rich repeat pyrin domain– containing 1B (Nlrp1b) inflammasome in the intestinal epithelium
Characterizing the nucleotide-binding domain leucine-rich repeat pyrin domain– containing 1B (Nlrp1b) inflammasome in the intestinal epithelium
批准号:
466750
负责人:
Mazzone Ryan J
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-12-01 至 2022-12-01
中文摘要
排列在肠道内的上皮细胞不仅在营养吸收中起作用,而且还作为保护免受微生物感染的重要屏障。在这些细胞中,NOD样受体(NLR)作为先天性的哨兵,
英文摘要
The epithelial cells that line the intestine not only function in nutrient absorption, but also serve as a crucial barrier that protects against microbial infection. Within these cells, NOD-like receptors (NLRs) act as innate sentinels that respond to spe
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