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Age-related changes to lymph node microarchitecture and impacts on T cell responses

Age-related changes to lymph node microarchitecture and impacts on T cell responses
与年龄相关的淋巴结微结构变化及其对 T 细胞反应的影响
批准号：
466763
负责人：
Bhagrath Aanya
金额：
$1.27万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-12-01 至 2022-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=466763&lang=en
关键词：
Dna Damage Fibroblastic Reticular Cells Immunosenescence Lymph Nodes Machine Learning Algorithms Mechanical Stiffness Nuclear Envelope Quantitative Imaging Stromal Cells T Cells

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中文摘要
翻译
COVID-19疫情表明，老年人因感染而出现严重症状的风险要高得多。这部分是由于T细胞的反应性降低，T细胞是一种保护身体免受外来入侵者侵害的免疫细胞，
英文摘要
The COVID-19 pandemic has illustrated that elderly people are at much higher risk of developing severe symptoms from infection. This is partly due to reduced responsiveness of T cells, a type of immune cell that protects the body from foreign invaders, su
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