Exploring the role of endogenous TDP-43 SUMOylation in mice: Implications for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Exploring the role of endogenous TDP-43 SUMOylation in mice: Implications for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
批准号:
480737
负责人:
Part Caroline E
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-12-01 至 2022-12-01
中文摘要
每年有数以千计的加拿大人死于肌萎缩侧索硬化症(ALS):一种以运动神经元死亡为特征的进行性神经退行性疾病。患者运动功能受损,通常在确诊后2-5年内因呼吸而死亡
英文摘要
Thousands of Canadians die annually from Amyotrophic lateral sclerosis (ALS): a progressive neurodegenerative disease characterized by death of motor neurons. Patients suffer impaired motor function and typically die within 2-5 years of diagnosis to respi
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