Novel contrasting functions of RNF168 and RNF169 in breast cancer and therapeutic implications.
Novel contrasting functions of RNF168 and RNF169 in breast cancer and therapeutic implications.
RNF168 和 RNF169 在乳腺癌中的新颖对比功能及其治疗意义。
批准号：
462070
负责人：
Hakem Razqallah
金额：
$69.66万
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
未结题
起止时间：
2022-03-01 至 2027-03-01
中文摘要
翻译
了解乳腺癌的根本原因对于改进其治疗是至关重要的。尽管在过去的几十年里，在识别推动乳腺癌发展的机制方面取得了进展，但仍迫切需要发现为其量身定做的新疗法
英文摘要
Understanding the root causes of breast cancer is essential to improve its therapy. Despite advances made in the past decades in identifying mechanisms that drive breast cancer development, there is an urgent need to discover novel therapies tailored for
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会议论文
Targeting transcription-replication conflicts as vulnerabilities in BRCA1 mutant and homologous recombination-deficient breast and ovarian cancers
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批准号：469737
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项目类别：Operating Grants
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资助金额：$69.66万
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财政年份：2022
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负责人：Hakem Razqallah
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依托单位：
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依托单位：
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批准号：313498
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项目类别：Operating Grants
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资助金额：$136.86万
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财政年份：2014
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负责人：Hakem Razqallah
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依托单位：
Examination of the effect of posttranslational modifications of 53BP1 in development and diseases
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批准号：226562
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项目类别：Operating Grants
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资助金额：$33.69万
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财政年份：2011
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负责人：Hakem Razqallah
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依托单位：
海外基金
