Granzyme B mediates degradation of dermal-epidermal junction proteins in Stevens-Johnson syndrome and toxic epidermal necrolysis
Granzyme B mediates degradation of dermal-epidermal junction proteins in Stevens-Johnson syndrome and toxic epidermal necrolysis
批准号:
486290
负责人:
Lane Michael M
金额:
$1.27万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-12-01 至 2023-12-01
中文摘要
史蒂文斯-约翰逊综合征(SJS)和中毒性表皮坏死松解症(TEN)是涉及皮肤剥落和起泡的严重疾病。SJS的严重程度较低,而TEN的结局更差。虽然这些疾病很罕见,但受其折磨的人
英文摘要
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious diseases that involve peeling and blistering of the skin. SJS is on the less serious side while TEN has worse outcomes. While these diseases are rare, those afflicted by them
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