Novel mechanism of FNAIT: effect of maternal anti-aIIb antibodies on hematopoietic stem cells.
Novel mechanism of FNAIT: effect of maternal anti-aIIb antibodies on hematopoietic stem cells.
批准号:
488150
负责人:
Khoury Christopher J
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-12-01 至 2023-12-01
中文摘要
胎儿和新生儿同种免疫性血小板减少症(FNAIT)是一种严重的出血性疾病,新生儿发病率为0.5-1.5/1000。它是由母体对胎儿、父系衍生的某些血小板糖蛋白基因多态性的免疫反应引起的。反3个Me
英文摘要
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is serious bleeding disorder affecting 0.5-1.5/1000 newborn neonate. It is caused by maternal immmune responses to fetal, paternally-derived polymorphisms on certain platelet glycoproteins. Anti-ß3 me
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