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Studying nucleolar RNA polymerase II and its ncRNAs to restrain cancer

Studying nucleolar RNA polymerase II and its ncRNAs to restrain cancer
研究核仁 RNA 聚合酶 II 及其 ncRNA 抑制癌症
批准号:
479043
负责人:
Mekhail Karim
金额:
$74.96万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-03-01 至 2028-03-01

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中文摘要
翻译
人体由数万亿个细胞组成,细胞的寿命取决于促进或阻碍生长的力量之间的平衡。一方面,早期细胞停滞被称为衰老,如果持续下去,它会导致细胞过早衰老
英文摘要
The human body is composed of trillions of cells, the longevity of which depends on the balance between forces that promote or stall growth. On the one hand, early cell stalling is known as senescence, and it can lead to premature cellular aging if kept u
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Control of genome stability by a nanotubular nuclear envelope network
  • 批准号:
    451893
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.6万
  • 财政年份:
    2021
  • 负责人:
    Mekhail Karim
  • 依托单位:
Pol II and its R-loops in the control of rDNA and genome stability
  • 批准号:
    380532
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.6万
  • 财政年份:
    2018
  • 负责人:
    Mekhail Karim
  • 依托单位:
Cooperation between DIMs and motor proteins in DSB mobility-dependent repair
  • 批准号:
    368354
  • 项目类别:
    Operating Grants
  • 资助金额:
    $46.37万
  • 财政年份:
    2017
  • 负责人:
    Mekhail Karim
  • 依托单位:
Pol II and its RNA-DNA hybrids in the control of rDNA and genome instability
  • 批准号:
    379018
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2017
  • 负责人:
    Mekhail Karim
  • 依托单位:
海外基金