Defining the molecular assembly mechanism of bacterial amyloid from single protein molecules to mature fibrils
Defining the molecular assembly mechanism of bacterial amyloid from single protein molecules to mature fibrils
批准号:
494840
负责人:
Dee Derek R
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
已结题
起止时间:
2023-09-01 至 2024-09-01
中文摘要
许多细菌可以形成一种称为生物膜的致密基质,帮助它们附着在表面并提供保护,帮助它们生存。生物膜的一个关键结构成分是淀粉样纤维,即由数千个蛋白质分子组成的蛋白质聚集体。
英文摘要
Many bacteria can form a dense matrix known as biofilm that helps them attach to surfaces and offers protection, aiding their survival. A key structural component of biofilm are amyloid fibrils, protein aggregates comprised of thousands of protein molecul
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