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Targeting metabolic vulnerabilities in childhood cancers using immunotherapy

Targeting metabolic vulnerabilities in childhood cancers using immunotherapy
使用免疫疗法针对儿童癌症的代谢脆弱性
批准号:
489753
负责人:
Sorensen Poul H
金额:
$69.66万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2028-09-01

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中文摘要
翻译
尤文肉瘤(EwS)是第二常见的儿童骨肉瘤,是一种侵袭性肿瘤,主要影响儿童,青少年和年轻人。当EwS肿瘤细胞扩散到身体的其他部位时,称为转移,生存率急剧下降。
英文摘要
Ewing sarcoma (EwS), the 2nd most common childhood bone sarcoma, is an aggressive tumour that primarily affects children, adolescents, and young adults. When EwS tumor cells spread to other parts of the body, known as metastasis, survival is drastically d
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会议论文
Targeting the tumour cell stress response in high-risk childhood cancers
  • 批准号:
    312683
  • 项目类别:
    Operating Grants
  • 资助金额:
    $167.64万
  • 财政年份:
    2014
  • 负责人:
    Sorensen Poul H
  • 依托单位:
The Hace1 tumour suppressor--a novel regulator of the oxidative stress response
Regulation of fusion oncoprotein stability by the IGF1 receptor axis
The Canadian Pediatric Cancer Genome Consortium: Translating next-generation sequencing technologies into improved therapies for high-risk childhood cancer
  • 批准号:
    224077
  • 项目类别:
    Operating Grants
  • 资助金额:
    $36.43万
  • 财政年份:
    2010
  • 负责人:
    Sorensen Poul H
  • 依托单位:
海外基金