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Targeting the translesion synthesis pathway as a potential therapeutic strategy in chemoresistant and late stage cancers

Targeting the translesion synthesis pathway as a potential therapeutic strategy in chemoresistant and late stage cancers
靶向跨损伤合成途径作为化疗耐药和晚期癌症的潜在治疗策略
批准号:
495243
负责人:
White Justin M
金额:
$0.11万
依托单位国家:
加拿大
项目类别:
财政年份:
2023
资助国家:
加拿大
项目状态:
已结题
起止时间:
2023-10-01 至 2024-10-01

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中文摘要
翻译
许多化疗和癌症治疗策略旨在引入DNA损伤,理想情况下是在癌细胞而不是正常的健康细胞内。细胞可以利用许多途径来克服这种损伤,其中一种称为反式
英文摘要
Many chemotherapies and cancer treatment strategies aim to introduce DNA damage, ideally within the cancer cells and not normal, healthy cells. There are many pathways that cells can leverage to overcome this kind of damage, one of which is known as trans
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会议论文
Therapy induced hypermutation to stimulate immune responses in recurrent cancer
  • 批准号:
    415354
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2018
  • 负责人:
    White Justin M
  • 依托单位:
海外基金