Parity differentially influences neuroplasticity and neuroinflammation at middle age depending on APOEe4 genotype
Parity differentially influences neuroplasticity and neuroinflammation at middle age depending on APOEe4 genotype
批准号:
495235
负责人:
Lee Bonnie
金额:
$0.15万
依托单位国家:
加拿大
项目类别:
财政年份:
2023
资助国家:
加拿大
项目状态:
已结题
起止时间:
2023-10-01 至 2024-10-01
关键词:
中文摘要
与男性相比,女性患阿尔茨海默病(AD)的终生风险更高,症状也更明显。APOEe4等位基因是阿尔茨海默病最强的遗传危险因素,有趣的是,携带APOEe4等位基因的女性患阿尔茨海默病的风险和负担高于携带APOEe4等位基因的女性
英文摘要
Females have a higher lifetime risk and show greater symptoms of Alzheimer's disease (AD) than males. The strongest genetic risk factor for AD is having APOEe4 alleles, and interestingly, females with APOEe4 alleles show greater risk and burden of AD than
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会议论文
The impact of motherhood and APOE genotype on the aging brain
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批准号:400147
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项目类别:
-
资助金额:$0.07万
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财政年份:2019
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负责人:Lee Bonnie
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依托单位:
Counselling the Relational Unit in Addiction Treatment
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批准号:289467
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项目类别:Miscellaneous Programs
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资助金额:$1.63万
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财政年份:2013
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负责人:Lee Bonnie
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依托单位: