The Functional Importance of the Actin Severing Protein Adseverin during Early and Late Phase Osteoclastogenesis
The Functional Importance of the Actin Severing Protein Adseverin during Early and Late Phase Osteoclastogenesis
批准号:
201040
负责人:
Hassanpour Siavash
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-02-01 至 2011-02-01
中文摘要
破骨细胞形成或破骨细胞生成需要NF κ B受体激活剂配体(RANKL)刺激的破骨细胞前体的迁移和融合,以形成大的多核成熟破骨细胞。同样,成熟的破骨细胞通过
英文摘要
Osteoclast formation, or osteoclastogenesis, requires the Receptor Activator of NFkB Ligand (RANKL)-stimulated migration and fusion of osteoclast precursors to form large multinucleated mature osteoclasts. Likewise, mature osteoclasts degrade bone through
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