combi.pl: a computer program to combine data sets with inconsistent microsatellite marker allele size information

combi.pl: a computer program to combine data sets with inconsistent microsatellite marker allele size information
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Combi PL:一种计算机程序,用于将数据集与不一致的微卫星标记等位基因大小信息组合起来

DOI:
10.1111/j.1471-8286.2007.02011.x
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发表时间:
2007
影响因子:
7.7
通讯作者:
D.G. Bradley
D.G. Bradley
中科院分区:
生物学1区
文献类型:
--
作者:
H. Täubert;D.G. Bradley

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将两个数据集与来自重叠微卫星标记的等位基因信息相结合通常是可取的,特别是在存在大量已发表数据的群体遗传学研究中。当在不同的实验室进行基因分型时,等位基因大小判定可能不一致。我们的方法通过使用最大似然理论在研究中分配等位基因大小来解决这个问题。使用样品和标记物中的数据重叠,计算每个重叠标记物在两个研究之间的等位基因偏移,并产生包含一致等位基因的等位基因频率的单个文件。该程序(combi.pl)是用PERL编写的,可在http://data40.uni-tz.gwdg.de/datahtaeube上找到。
Combining two data sets with allele information from overlapping microsatellite markers is often desirable, particularly in population genetic studies where a substantial body of published data exists. When genotyping is performed in different laboratories, allele size calling may not be presumed to be consistent. Our approach solves this problem by assigning allele sizes across studies using maximum‐likelihood theory. Using data overlaps in samples and markers, allele shifts between two studies are calculated for each overlapping marker and a single file containing allele frequencies of consistent alleles is produced. The program (combi.pl) is written in PERL and available at http://data40.uni‐tz.gwdg.de/~htaeube.
DOI: 10.1128/jcm.02136-06
发表时间: 2007-02-01
影响因子: 9.4
作者:
Pasqualotto, Alessandro C.;Denning, David W.;Anderson, Michael J.
通讯作者: Anderson, Michael J.
DOI: --
发表时间: 2003
期刊:
影响因子: --
作者:
Magali SanCristobal;K. Li;L. Andersson;M. A. M. Groenen;G. Plastow;Claude Chevalet;S. Blott;L. Huang;Chris Haley;R. Cardellino;N. Li
通讯作者: N. Li
DOI: 10.1111/j.1365-2052.2005.01385.x
发表时间: 2006-06-01
期刊: ANIMAL GENETICS
影响因子: 2.4
作者:
SanCristobal, M.;Chevalet, C.;Cardellino, R.
通讯作者: Cardellino, R.