Dietary supplement use by older adults with chronic venous leg ulcers: A retrospective, descriptive study.

Dietary supplement use by older adults with chronic venous leg ulcers: A retrospective, descriptive study.
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DOI:
10.1111/wrr.12821
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发表时间:
2020-07
影响因子:
2.9
通讯作者:
McDaniel, Jodi C.
McDaniel, Jodi C.
中科院分区:
医学3区
文献类型:
--
作者:
McDaniel, Jodi C.

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近 70% 的美国老年人表示每天使用 ≥1 种膳食补充剂 (DS)。虽然 DS 可能对健康有益,但如果服用不当,则存在毒性或有害的药物补充剂相互作用的风险。使用 DS 的患有慢性伤口的老年人发生不良药物补充剂相互作用的风险增加,因为他们通常患有需要多药管理的合并症。然而,尚无研究评估 DS 在该人群中的使用情况。这项回顾性试点研究的目的是描述患有慢性腿部静脉溃疡 (CVLU) 的老年人样本 (n = 40) 对 DS 的使用情况,这些老年人参加了一项测试补充鱼油对伤口愈合影响的临床试验。在基线时,研究人员协助所有参与者完成有关 DS 使用的电子调查问卷。使用描述性统计来表征数据。 40 名参与者中有 25 名 (62.5%) 报告每天服用 ≥1 DS。 DS 用户的平均年龄为 65.16 岁 (SD = 8.51),大多数是男性 (64.0%)、白人 (68.0%),并且至少受过大学教育 (72.0%)。 15 名 (60.0%) 报告每天服用 1-2 次 DS,10 名 (40.0%) 报告每天服用 ≥3 次。最常报告使用的 DS 是多种维生素/矿物质复合物 (60.0%)、维生素 D (36.0%)、复合维生素 B (28.0%) 和钙 (28.0%)。使用DS的原因是维持或改善健康(44.0%)、提高骨密度(12%)和增强免疫系统(12%)。补充剂使用者报告平均每天服用 9.12 (SD = 6.46) 种处方药,21 人 (84.0%) 报告有 ≥3 种慢性健康问题。总之,慢性伤口患者样本中 DS 的使用率很高。此外,DS 用户报告称在 DS 的同时使用了多种处方药(2-23 次/天)。虽然患有 CVLU 的老年人可能会受益于靶向 DS 治疗,但最佳实践是监测其 DS 使用情况以降低不良药物补充剂相互作用的风险。
Nearly 70% of older adults in the U.S. report using ≥1 dietary supplements (DSs) daily. While DSs may have health benefits, there is risk for toxicity or harmful drug-supplement interactions if not taken correctly. Older adults with chronic wounds who use DSs are at increased risk of adverse drug-supplement interactions because they usually have comorbidities requiring polypharmacy management. However, no studies have evaluated DS use in this population. The aim of this retrospective pilot study was to describe DS use by a sample of older adults (n = 40) with chronic venous leg ulcers (CVLUs) who participated in a clinical trial testing the effects of fish oil supplementation on wound healing. At baseline, study personnel assisted all participants in completing an electronic questionnaire about DS use. Descriptive statistics were used to characterize the data. Twenty-five of the 40 participants (62.5%) reported taking ≥1 DS daily. On average, DS users were 65.16 years (SD = 8.51) and the majority were men (64.0%), white (68.0%), and had at least some college education (72.0%). Fifteen (60.0%) reported taking 1–2 DSs/day, and 10 (40.0%) reported taking ≥3/day. The most frequently reported DSs used were multivitamin/mineral complex (60.0%), vitamin D (36.0%), vitamin B complex (28.0%) and calcium (28.0%). Reasons for using DSs were to maintain or improve health (44.0%), improve bone density (12%), and boost the immune system (12%). Supplement users reported consuming an average of 9.12 (SD = 6.46) prescription drugs daily and 21 (84.0%) reported ≥3 chronic health conditions. In summary, DS use in this sample of chronic wound patients was high. Moreover, DS users reported using multiple prescription drugs (2–23/day) concomitantly with DSs. While older adults with CVLUs may benefit from targeted DS therapy, monitoring their DS use to reduce risk for adverse drug-supplement interactions is best practice.
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