Bioimage informatics for experimental biology.

Bioimage informatics for experimental biology.
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DOI:
10.1146/annurev.biophys.050708.133641
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发表时间:
2009
影响因子:
12.4
通讯作者:
OME Consortium
OME Consortium
中科院分区:
生物学1区
文献类型:
--
作者:
Swedlow JR;Goldberg IG;Eliceiri KW;OME Consortium

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在过去的二十年里,光学显微镜取得了巨大的进步,多维成像推动了现代生物学的革命。据报道,新的数据采集方法的开发是频繁的,但这些新的复杂数据集所带来的重大数据管理和分析挑战在很大程度上仍未解决。与基因组生物信息学的成熟领域一样,中央数据库现在是,将来也将是关键资源,但各个实验室迫切需要信息学工具来帮助管理、共享、可视化和分析图像数据。在这篇文章中,我们介绍了生物图像信息学社区最近为应对这些挑战所做的努力,并讨论了我们自己对生物图像信息学解决方案未来发展的愿景。
Over the last twenty years there have been great advances in light microscopy with the result that multi-dimensional imaging has driven a revolution in modern biology. The development of new approaches of data acquisition are reportedly frequently, and yet the significant data management and analysis challenges presented by these new complex datasets remains largely unsolved. Like the well-developed field of genome bioinformatics, central repositories are and will be key resources, but there is a critical need for informatics tools in individual laboratories to help manage, share, visualize, and analyze image data. In this article we present the recent efforts by the bioimage informatics community to tackle these challenges and discuss our own vision for future development of bioimage informatics solution.
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