Tactile, gustatory, and visual biofeedback stimuli modulate neural substrates of deglutition.
Tactile, gustatory, and visual biofeedback stimuli modulate neural substrates of deglutition.
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触觉，味觉和视觉生物反馈刺激调节脱发的神经底物。
DOI：
10.1016/j.neuroimage.2011.08.022
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发表时间：
2012-01-16
期刊：
影响因子：
5.7
通讯作者：
Joel, Suresh
中科院分区：
文献类型：
--
作者：
Humbert, Ianessa A.;Joel, Suresh
它已被公认，吞咽运动学修改与不同形式的外源性和内源性输入，但基本的神经基板与这些影响在很大程度上是未知的。我们的目的是确定吞咽BOLD反应是否与整个年龄段的健康成年人的饮水（对照）相比，通过增强的感觉方式（味觉、皮肤电刺激和视觉生物反馈）进行调节。还检查了每种感觉条件下的习惯化和致敏性。我们的主要发现是，每种感觉吞咽条件激活吞咽皮层网络的组件，加上与特定的感觉方式（即主要是额叶运动规划和整合区与视觉条件）相关的区域。总的来说，在感觉模态中，前额叶是最常见的活动。我们还讨论了BOLD信号的逐渐增加和减少与每种条件下的重复曝光。我们的结论是，刺激和意图为基础的输入有独特的皮层吞咽网络相对于他们的方式。这一科学贡献推进了我们对正常吞咽皮层控制机制的理解，并有可能影响这些模式在神经源性吞咽困难治疗中的临床应用。
It has been well established that swallowing kinematics are modified with different forms of exogenous and endogenous input, however the underlying neural substrates associated with these effects are largely unknown. Our objective was to determine whether the swallowing BOLD response is modulated with heightened sensory modalities (taste, cutaneous electrical stimulation, and visual biofeedback) compared to water ingestion (control) in healthy adults across the age span. Habituation and sensitization were also examined for each sensory condition. Our principal findings are that each sensory swallowing condition activated components of the swallowing cortical network, plus regions associated with the particular sensory modality (i.e. primarily frontal motor planning and integration areas with visual condition). Overall, the insula was most commonly active among the sensory modalities. We also discuss gradual increases and decreases in BOLD signal with repeated exposures for each condition. We conclude that both stimulus- and intention-based inputs have unique cortical swallowing networks relative to their modality. This scientific contribution advances our understanding of the mechanisms of normal swallowing cortical control and have the potential to impact clinical uses of these modalities in treatments for neurogenic dysphagia.
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DOI：
10.1152/ajpgi.00461.2006
发表时间：
2007-07-01
影响因子：
4.5
作者：
Coen, Steven J.;Gregory, Lloyd J.;Aziz, Qasim
通讯作者：
Aziz, Qasim
影响因子：
3.5
作者：
Cerf-Ducastel, B;Ven de Moortele, PF;Faurion, A
通讯作者：
Faurion, A
影响因子：
2.5
作者：
PAUS, T;PETRIDES, M;MEYER, E
通讯作者：
MEYER, E
DOI：
10.1044/jshr.3705.1041
发表时间：
1994-10-01
期刊：
JOURNAL OF SPEECH AND HEARING RESEARCH
影响因子：
--
作者：
BISCH, EM;LOGEMANN, JA;LAZARUS, CL
通讯作者：
LAZARUS, CL
DOI：
10.1044/1092-4388(2003/076
发表时间：
2003-08-01
影响因子：
2.6
作者：
Ding, RY;Logemann, JA;Rademaker, AW
通讯作者：
Rademaker, AW