The flavonoid GL‐V9 alleviates liver fibrosis by triggering senescence by regulating the transcription factor GATA4 in activated hepatic stellate cells
The flavonoid GL‐V9 alleviates liver fibrosis by triggering senescence by regulating the transcription factor GATA4 in activated hepatic stellate cells
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类黄酮 GL-V9 通过调节活化的肝星状细胞中的转录因子 GATA4 来引发衰老,从而减轻肝纤维化
DOI:
10.1111/bph.15997
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发表时间:
2022-12
影响因子:
7.3
通讯作者:
Lu Na
中科院分区:
文献类型:
--
作者:
Zhao Jiawei;Bai Dongsheng;Qi Lei;Cao Wangjia;Du Jiaying;Gu Chunyang;Zhou Chen;Gao Yuan;Zhang Lulu;Zhao Yue;Lu Na
Liver fibrosis is a critical risk factor for the progression from chronic liver injury to hepatocellular carcinoma. Clinically, there is a lack of therapeutic drugs for liver fibrosis. Previous studies have confirmed that GL‐V9, a newly synthesized flavon
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影响因子:
64.5
作者:
López-Otín C;Blasco MA;Partridge L;Serrano M;Kroemer G
通讯作者:
Kroemer G
影响因子:
13.5
作者:
Rolando Hernández;Muñoz;M. Díaz;Verónica López;F. López;Barrera;L. Yáñez;S. Vidrio;Alberto Aranda;Fraustro;V. C. Sánchez
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影响因子:
7.2
作者:
Zhao, Yue;Guo, Qinglong;Lu, Na
通讯作者:
Lu, Na
影响因子:
7.3
作者:
通讯作者:
--
影响因子:
16.1
作者:
Higashi T;Friedman SL;Hoshida Y
通讯作者:
Hoshida Y