Exposure-based cognitive-behavioral treatment of PTSD in adults with schizophrenia or schizoaffective disorder: a pilot study.

Exposure-based cognitive-behavioral treatment of PTSD in adults with schizophrenia or schizoaffective disorder: a pilot study.
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DOI:
10.1016/j.janxdis.2009.02.005
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发表时间:
2009-06
影响因子:
10.3
通讯作者:
Knapp RG
Knapp RG
中科院分区:
医学2区
文献类型:
--
作者:
Frueh BC;Grubaugh AL;Cusack KJ;Kimble MO;Elhai JD;Knapp RG

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在一项开放试验设计中,患有创伤后应激障碍(PTSD)和精神分裂症或情感障碍的成年人(n = 20)通过为期11周的PTSD认知行为干预治疗,包括教育,焦虑管理治疗,社交技能培训和暴露治疗,在社区精神卫生中心提供。结果提供了初步的希望,有效治疗PTSD的成年精神分裂症或情感障碍,特别是在治疗完成者(n = 13)。数据显示PTSD症状显著改善,并在3个月随访时保持。此外,13名完成者中有12名不再符合PTSD标准或被认为是治疗反应者。其他目标领域的临床结果(例如,愤怒,一般心理健康)也得到改善,并在3个月随访时得到维持。参与者表现出很高的治疗满意度,没有不良事件。在抑郁、一般焦虑或身体健康状况方面没有显著改善。未来的方向包括需要随机对照试验和传播工作。
In an open trial design, adults (n = 20) with posttraumatic stress disorder (PTSD) and either schizophrenia or schizoaffective disorder were treated via an 11-week cognitive-behavioral intervention for PTSD that consisted of education, anxiety management therapy, social skills training, and exposure therapy, provided at community mental health centers. Results offer preliminary hope for effective treatment of PTSD among adults with schizophrenia or schizoaffective disorder, especially among treatment completers (n = 13). Data showed significant PTSD symptom improvement, maintained at 3-month follow-up. Further, 12 of 13 completers no longer met criteria for PTSD or were considered treatment responders. Clinical outcomes for other targeted domains (e.g., anger, general mental health) also improved and were maintained at 3-month follow-up. Participants evidenced high treatment satisfaction, with no adverse events. Significant improvements were not noted on depression, general anxiety, or physical health status. Future directions include the need for randomized controlled trials and dissemination efforts.
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影响因子: 5.9
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