Imaging in gout--what can we learn from MRI, CT, DECT and US?
Imaging in gout--what can we learn from MRI, CT, DECT and US?
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DOI：
10.1186/ar3489
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发表时间：
2011
影响因子：
4.9
通讯作者：
Dalbeth N
中科院分区：
文献类型：
--
作者：
McQueen FM;Doyle A;Dalbeth N
痛风的高级成像有许多令人兴奋的新应用。这些模式采用多平面成像，并允许计算机三维渲染的骨骼和关节（包括痛风石），并具有电子数据存储的优势，供以后检索。高分辨率计算机断层扫描通过研究骨侵蚀和痛风石之间的关系，在探索痛风的病理学方面特别有帮助。磁共振成像和超声波可以显示痛风性关节病的炎症性质，揭示滑膜和软组织炎症，并可以提供有关痛风石成分和血管分布的信息。双能计算机断层扫描是一种新的方式，能够识别痛风石的化学成分，甚至揭示小的隐藏痛风石沉积。正在研究所有模式在诊断中的潜在作用，并可能在不可能从关节中抽吸出尿酸盐晶体的患者中具有重要的临床应用。成像还可以提供结果测量，如痛风石体积的变化，用于监测对降尿酸治疗的反应，这是临床试验环境中的重要应用。
There are many exciting new applications for advanced imaging in gout. These modalities employ multiplanar imaging and allow computerized three-dimensional rendering of bone and joints (including tophi) and have the advantage of electronic data storage for later retrieval. High-resolution computed tomography has been particularly helpful in exploring the pathology of gout by investigating the relationship between bone erosions and tophi. Magnetic resonance imaging and ultrasonography can image the inflammatory nature of gouty arthropathy, revealing synovial and soft tissue inflammation, and can provide information about the composition and vascularity of tophi. Dual-energy computerized tomography is a new modality that is able to identify tophi by their chemical composition and reveal even small occult tophaceous deposits. All modalities are being investigated for their potential roles in diagnosis and could have important clinical applications in the patient for whom aspiration of monosodium urate crystals from the joint is not possible. Imaging can also provide outcome measures, such as change in tophus volume, for monitoring the response to urate-lowering therapy and this is an important application in the clinical trial setting.
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影响因子：
27.4
作者：
Choi, H. K.;Al-Arfaj, A. M.;Nicolaou, S.
通讯作者：
Nicolaou, S.
影响因子：
--
作者：
Dalbeth, Nicola;Smith, Timothy;Cornish, Jillian
通讯作者：
Cornish, Jillian
影响因子：
27.4
作者：
Gerster, JC;Landry, M;Meuwly, JY
通讯作者：
Meuwly, JY
影响因子：
27.4
作者：
Gardner, H;McQueen, F
通讯作者：
McQueen, F
DOI：
10.1177/107110078200200604
发表时间：
1982-01-01
期刊：
FOOT & ANKLE
影响因子：
--
作者：
GUERRA, J;RESNICK, D
通讯作者：
RESNICK, D