Transition to retirement and risk of cardiovascular disease: prospective analysis of the US health and retirement study.

Transition to retirement and risk of cardiovascular disease: prospective analysis of the US health and retirement study.
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DOI:
10.1016/j.socscimed.2012.04.004
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发表时间:
2012-08
影响因子:
5.4
通讯作者:
Kawachi, Ichiro
Kawachi, Ichiro
中科院分区:
医学2区
文献类型:
--
作者:
Moon, J. Robin;Glymour, M. Maria;Subramanian, S. V.;Avendano, Mauricio;Kawachi, Ichiro

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从工作到退休的过渡可能对健康有益,也可能有害。我们调查了退休过渡与卒中和心肌梗死(MI)风险之间的关系。我们对1998年美国健康与退休研究中年龄在50岁以上的全职工作且无主要心血管疾病的参与者(n= 5422)进行了随访,随访时间长达10年,以过渡到完全退休,并自我报告或代理报告中风或心肌梗塞(CVD; 665例事件)。我们使用离散时间生存分析来比较完全退休人群和全职工作人群的心血管疾病发病率。为了区分短期和长期风险,我们比较了退休后第一年的协会和退休后2年以上的估计。在调整了年龄、性别、儿童期和成年SES、行为和合并症的完整模型中,与留在全职劳动力中的人相比,退休与CVD发病几率升高相关(OR=1.40, 95% CI: 1.04, 1.90)。退休后一年内心血管疾病发病率的优势比为1.55 (95% CI: 1.03, 2.33)。从退休后第二年开始,与仍在工作的人相比,退休人员患心血管疾病的风险略微升高(OR=1.35; 95% CI: 0.96, 1.91)。虽然某些亚组的置信区间很宽,但性别或社会经济地位之间没有显著的相互作用。结果表明,退休后心血管疾病风险增加。
Transitioning from work to retirement could be either beneficial or harmful for health. We investigated the association between transition to retirement and risk of stroke and myocardial infarction (MI). We followed US Health and Retirement Study participants age 50+ working full-time for pay and free of major cardiovascular disease (n=5,422) in 1998 up to 10 years for transition to full retirement and self- or proxy-report of either stroke or MI (CVD; 665 events). We used discrete-time survival analysis to compare the CVD incidence for the fully retired versus the full-time working population. To distinguish short-term from long-term risks, we compared the association in the first year after retirement to estimates 2+ years after retirement. In the full model adjusting for age, sex, childhood and adult SES, behavior, and co-morbidities, being retired was associated with elevated odds of CVD onset (OR=1.40, 95% CI: 1.04, 1.90) compared to those remaining in the full-time labor force. The odds ratio for CVD incidence within the first year of retirement was 1.55 (95% CI: 1.03, 2.33). From the second year post-retirement and thereafter, the retired had marginally elevated risk of CVD compared to those still working (OR=1.35; 95% CI: 0.96, 1.91). Although confidence intervals were wide for some subgroups, there were no significant interactions by sex or socioeconomic status. Results suggest that CVD risk is increased after retirement.
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