Effect of retirement on major chronic conditions and fatigue: French GAZEL occupational cohort study.
Effect of retirement on major chronic conditions and fatigue: French GAZEL occupational cohort study.
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DOI：
10.1136/bmj.c6149
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发表时间：
2010-11-23
期刊：
影响因子：
--
通讯作者：
Kivimäki M
中科院分区：
文献类型：
--
作者：
Westerlund H;Vahtera J;Ferrie JE;Singh-Manoux A;Pentti J;Melchior M;Leineweber C;Jokela M;Siegrist J;Goldberg M;Zins M;Kivimäki M
目的：通过纵向分析，确定退休后是否会发生慢性疾病、抑郁症状和疲劳的风险变化。设计前瞻性研究，采用退休前7年至退休后7年的重复测量方法。背景：1989-2007年法国大型职业队列（GAZEL研究）。参与者有11246名男性和2858名女性。主要结局指标：呼吸系统疾病、糖尿病、冠心病和中风、精神疲劳和身体疲劳，在15年的观察期内每年通过自我报告测量；在四个时间点测量抑郁症状。结果每位受试者平均重复测量次数为12.1次。使用广义估计方程的重复测量逻辑回归显示，自我报告的呼吸系统疾病、糖尿病、冠心病和中风的累积患病率随着年龄的增长而增加，在退休前后这一趋势没有中断。相比之下，退休与精神疲劳（退休后一年与退休前一年的疲劳优势比为0.19,95%可信区间为0.18至0.21）和身体疲劳（0.27,0.26至0.30）的患病率大幅下降有关。抑郁症状也显著减少（0.60,0.53至0.67）。在退休前患有慢性病的人群中，退休前后疲劳程度的下降更为明显。结论：重复数据的纵向建模表明，退休不会改变患重大慢性病的风险，但与精神和身体疲劳以及抑郁症状的大幅减少有关，特别是在患有慢性病的人群中。
Objectives To determine, using longitudinal analyses, if retirement is followed by a change in the risk of incident chronic diseases, depressive symptoms, and fatigue. Design Prospective study with repeat measures from 7 years before to 7 years after retirement. Setting Large French occupational cohort (the GAZEL study), 1989-2007. Participants 11 246 men and 2858 women. Main outcome measures Respiratory disease, diabetes, coronary heart disease and stroke, mental fatigue, and physical fatigue, measured annually by self report over the 15 year observation period; depressive symptoms measured at four time points. Results The average number of repeat measurements per participant was 12.1. Repeated measures logistic regression with generalised estimating equations showed that the cumulative prevalence of self reported respiratory disease, diabetes, and coronary heart disease and stroke increased with age, with no break in the trend around retirement. In contrast, retirement was associated with a substantial decrease in the prevalence of both mental fatigue (odds ratio for fatigue one year after versus one year before retirement 0.19, 95% confidence interval 0.18 to 0.21) and physical fatigue (0.27, 0.26 to 0.30). A major decrease was also observed in depressive symptoms (0.60, 0.53 to 0.67). The decrease in fatigue around retirement was more pronounced among people with a chronic disease before retirement. Conclusions Longitudinal modelling of repeat data showed that retirement did not change the risk of major chronic diseases but was associated with a substantial reduction in mental and physical fatigue and depressive symptoms, particularly among people with chronic diseases.
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DOI：
10.1111/j.1532-5415.2008.01957.x
发表时间：
2008-10-01
影响因子：
6.3
作者：
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通讯作者：
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影响因子：
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作者：
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DOI：
10.1093/geronb/52b.3.p110
发表时间：
1997-05-01
影响因子：
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影响因子：
6.3
作者：
Mein, G.;Martikainen, P.;Marmot, M.
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DOI：
10.1007/s00420-001-0294-0
发表时间：
2002-04-01
影响因子：
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作者：
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