Decreasing age disparities in syphilis and gonorrhea incidence rates in the United States, 1981--2005.

Decreasing age disparities in syphilis and gonorrhea incidence rates in the United States, 1981--2005.
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1981 年-2005 年美国梅毒和淋病发病率的年龄差异不断缩小。

DOI:
10.1097/olq.0b013e31816a8dcd
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发表时间:
2008
影响因子:
3.1
通讯作者:
Miller,WilliamC
Miller,WilliamC
中科院分区:
医学4区
文献类型:
--
作者:
Miller,WilliamC

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在过去25年中,梅毒和淋病的发病率有所下降,但近年来,这一趋势正在逆转。1鉴于公共卫生部门为预防性传播感染和艾滋病毒感染做出了相当大的努力,这一历史性下降是意料之中的,但最近梅毒和淋病的增加令人不安。是什么导致了这些变化?细节、潜在的趋势和关系不那么明显。哪些群体正在发生变化?哪些群体对最近观察到的增长负责?在这一期的性传播疾病中,来自疾病控制和预防中心的Chesson等人2提供的数据表明,随着梅毒和淋病的发病率在过去25年中下降,这些发病率的年龄差距缩小了。性传播感染主要是青年感染。据推测,年轻人更有可能表现出更危险的性行为,从而更常见地获得性传播感染。淋病和梅毒的发病率在不同年龄组之间的差异是相当惊人的。对于梅毒,在整个1980年代,年轻人(15-29岁)报告的发病率大约是老年人(40-54岁)的三倍。Chesson等人2报告称,年轻成人的发生率仅略高于老年人。相比之下,与老年人相比,年轻人的淋病报告率仍然高出约10倍。尽管如此,这一差距与1980年代初相比已经大幅下降,当时年轻人的比率几乎高出16倍。我们可以从这些利率变化中学到什么?这些观察提出了什么新问题?
During the past 25 years, rates of syphilis and gonorrhea have declined, although in recent years, this trend has been reversing. 1 Given the considerable public health efforts to prevent sexually transmitted infections (STIs) and HIV infection, the historical decline was expected, but the more recent increases in syphilis and gonorrhea are disturbing. What is responsible for these changes? The details, the underlying trends and relationships, are less apparent. In which groups are changes occurring? What groups are responsible for the recently observed increases?In this issue of Sexually Transmitted Diseases, Chesson et al. 2 from the Centers for Disease Control and Prevention present data to suggest that as the rates of syphilis and gonorrhea declined during the past 25 years, the age disparity in these rates narrowed. STIs are predominantly infections of youth. Presumably, young adults are more likely to demonstrate riskier sexual behavior, and thereby, acquire STIs more commonly. The disparities in the rates of gonorrhea and syphilis across age groups are quite striking. For syphilis, reported rates in younger adults (aged 15–29 years) were roughly three times higher than in older adults (aged 40–54 years) throughout the 1980s. Chesson et al. 2 reported that rates in younger adults are only slightly higher than in older adults. In contrast, reported rates for gonorrhea remain approximately 10 times higher in younger adults, when compared with older adults. Nonetheless, this gap represents a substantial decline from the early 1980s when rates in young adults were nearly 16 times higher. What can we learn from these rate changes? What new questions do these observations raise?
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