Characteristics and Outcomes of 35 Breast Cancer Patients Infected With COVID-19.
Characteristics and Outcomes of 35 Breast Cancer Patients Infected With COVID-19.
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35 名感染 COVID-19 的乳腺癌患者的特征和结果
DOI：
10.3389/fonc.2020.570130
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发表时间：
2020
影响因子：
4.7
通讯作者：
Li Y
中科院分区：
文献类型：
--
作者：
Zhang B;Xie R;Hubert SM;Yu Y;Zhang Y;Lei X;Deng W;Chen J;Li Y
2019年12月以来，由严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引起的新型冠状病毒病(新冠肺炎)迅速席卷全球。在之前的研究中，感染新冠肺炎的癌症患者被认为比普通的新冠肺炎患者具有更高的疾病严重性和更高的死亡率。然而，由于有关新冠肺炎癌症患者的临床信息较少，支持这一结论的证据不足。目前，对新冠肺炎感染乳腺癌患者的临床资料进行分析的报道相当有限。因此，在这项回顾性研究中，我们描述了35例新冠肺炎乳腺癌患者的临床特点和预后，并以55例新冠肺炎非癌患者和81例新冠肺炎患者与其他类型癌症患者作为对照。我们的数据显示，新冠肺炎乳腺癌患者与普通新冠肺炎患者在疾病严重程度和预后方面没有差异，这与之前的研究形成了鲜明对比。此外，与其他类型的癌症患者相比，乳腺癌患者中无症状感染和轻度感染所占的比例要大得多。我们的结果表明乳腺癌患者的临床特征比其他类型的癌症患者要轻，但两组患者的预后没有显著差异。
Since December 2019, a novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly engulfed the world. Cancer patients infected with COVID-19 are considered to carry higher severity of the disease and higher mortality rate than common COVID-19 patients in previous studies. However, due to the poor clinical information on COVID-19 patients with cancer, the evidences that supported this conclusion are insufficient. At present, rather limited reports have analyzed the clinical data of breast cancer patients infected with COVID-19. Therefore, in this retrospective study, we described the clinical characteristics and the outcomes of 35 COVID-19 patients with breast cancer and compared 55 COVID-19 patients without cancer and 81 COVID-19 patients with other types of cancer as controls. Our data showed that there were no differences in disease severity and outcomes between the COVID-19 patients with breast cancer and the common COVID-19 patients, which was in contrast to previous studies. In addition, compared with other types of cancer patients, asymptomatic infections and mild cases among breast cancer patients made up a substantially larger proportion. Our results indicated that the clinical characteristics of breast cancer patients were milder than those of other types of cancer patients, but there were no significant differences in outcomes between the two groups.
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影响因子：
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