Towards patient-based cancer therapeutics.
Towards patient-based cancer therapeutics.
复制标题
DOI:
10.1038/nbt0910-904
复制
发表时间:
2010-09
影响因子:
46.9
通讯作者:
Posner, Bruce A.
中科院分区:
文献类型:
--
作者:
Schreiber, Stuart L.;Shamji, Alykhan F.;Clemons, Paul A.;Hon, Cindy;Koehler, Angela N.;Munoz, Benito;Palmer, Michelle;Stern, Andrew M.;Wagner, Bridget K.;Powers, Scott;Lowe, Scott W.;Guo, Xuecui;Krasnitz, Alex;Sawey, Eric T.;Sordella, Raffaella;Stein, Lincoln;Trotman, Lloyd C.;Califano, Andrea;Dalla-Favera, Riccardo;Ferrando, Adolfo;Iavarone, Antonio;Pasqualucci, Laura;Silva, Jose;Stockwell, Brent R.;Hahn, William C.;Chin, Lynda;DePinho, Ronald A.;Boehm, Jesse S.;Gopal, Shuba;Huang, Alan;Root, David E.;Weir, Barbara A.;Gerhard, Daniela S.;Zenklusen, Jean Claude;Roth, Michael G.;White, Michael A.;Minna, John D.;MacMillan, John B.;Posner, Bruce A.
A new approach to the discovery of cancer therapeutics is emerging that begins with the cancer patient. Genomic analysis of primary tumors is providing an unprecedented molecular characterization of the disease. The next step requires relating the genetic features of cancers to acquired gene and pathway dependencies and identifying small-molecule therapeutics that target them.
登录
查看更多内容
影响因子:
--
作者:
Workman P;Collins I
通讯作者:
Collins I
影响因子:
64.8
作者:
Zheng, Hongwu;Ying, Haoqiang;Yan, Haiyan;Kimmelman, Alec C.;Hiller, David J.;Chen, An-Jou;Perry, Samuel R.;Tonon, Giovanni;Chu, Gerald C.;Ding, Zhihu;Stommel, Jayne M.;Dunn, Katherine L.;Wiedemeyer, Ruprecht;You, Mingjian J.;Brennan, Cameron;Wang, Y. Alan;Ligon, Keith L.;Wong, Wing H.;Chin, Lynda;DePinho, Ronald A.
通讯作者:
DePinho, Ronald A.
影响因子:
64.5
作者:
Zender, Lars;Spector, Mona S.;Lowe, Scott W.
通讯作者:
Lowe, Scott W.
影响因子:
64.8
作者:
通讯作者:
--
影响因子:
15.9
作者:
Sos, Martin L.;Michel, Kathrin;Thomas, Roman K.
通讯作者:
Thomas, Roman K.