Current priorities for public health practice in addressing the role of human genomics in improving population health.
Current priorities for public health practice in addressing the role of human genomics in improving population health.
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DOI：
10.1016/j.amepre.2010.12.009
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发表时间：
2011-04
影响因子：
5.5
通讯作者：
St Pierre J
中科院分区：
文献类型：
--
作者：
Khoury MJ;Bowen MS;Burke W;Coates RJ;Dowling NF;Evans JP;Reyes M;St Pierre J
尽管人类基因组在多种具有公共卫生意义的疾病中的发现不断加速，但基于基因组学的个性化医疗保健和疾病预防的前景却滞后了。在资源有限的情况下，公共卫生机构必须继续专注于实施能够改善健康和预防疾病的计划。尽管如此，公共卫生在解决人类基因组学对人口健康的前景和陷阱方面发挥着重要而坚定的领导作用。这些努力不仅是为了实施基因组学中已知的方法来改善健康，而且是为了减少潜在的危害并创建未来获得健康益处所需的基础设施。
In spite of accelerating human genome discoveries in a wide variety of diseases of public health significance, the promise of personalized health care and disease prevention based on genomics has lagged behind. In a time of limited resources, public health agencies must continue to focus on implementing programs that can improve health and prevent disease now. Nevertheless, public health has an important and assertive leadership role in addressing the promise and pitfalls of human genomics for population health. Such efforts are needed not only to implement what is known in genomics to improve health but also to reduce potential harm and create the infrastructure needed to derive health benefits in the future.
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