The Video Head Impulse Test (vHIT) of Semicircular Canal Function - Age-Dependent Normative Values of VOR Gain in Healthy Subjects.
The Video Head Impulse Test (vHIT) of Semicircular Canal Function - Age-Dependent Normative Values of VOR Gain in Healthy Subjects.
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DOI：
10.3389/fneur.2015.00154
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发表时间：
2015
影响因子：
3.4
通讯作者：
Curthoys IS
中科院分区：
文献类型：
--
作者：
McGarvie LA;MacDougall HG;Halmagyi GM;Burgess AM;Weber KP;Curthoys IS
视频头脉冲测试（vHIT）现在被广泛用于测试的功能，每个半规管单独通过测量眼睛旋转响应突然头部旋转的平面上的运河。耳道充分性的主要量度是眼运动响应与头部运动刺激的比率，即，前庭眼反射（vestibulo-ocular reflex，VOR）然而，需要关于VOR增益如何受年龄以及头部速度影响的规范性数据，以允许将任何特定患者的反应与其年龄范围内的健康受试者的反应进行比较。在这项研究中，我们确定了所有六个半规管，VOR增益的标准值，为每个管在一个范围内的头部速度，健康受试者在每十年的生活。在10岁年龄段（10-19、20-29、30-39、40-49、50-59、60-69、70-79、80-89）的至少10名健康受试者的头部速度范围内测量所有根管的VOR增益。通过ICS脉冲原型系统测量了对小的、不可预测的、突然的头部旋转（头部脉冲）的补偿性眼动反应。同一个操作员将每一个脉冲传递给每个受试者。前庭-眼反射增益在高头部速度下降低，但在80- 89岁年龄组中基本不受年龄影响。头部旋转的两个方向之间存在一些小但系统性的差异，这似乎主要是由于在本研究中仅测量了右眼。这些结果被认为是最近的证据有关的年龄对VOR性能的影响。这些标准值允许将任何特定患者的结果与其年龄范围内的健康人的值进行比较，并且因此允许例如检测患者是否具有双侧前庭损失。VOR增益，直接测量的眼球运动响应头部旋转，似乎在很大程度上不受年龄的影响。
The video Head Impulse Test (vHIT) is now widely used to test the function of each of the six semicircular canals individually by measuring the eye rotation response to an abrupt head rotation in the plane of the canal. The main measure of canal adequacy is the ratio of the eye movement response to the head movement stimulus, i.e., the gain of the vestibulo-ocular reflex (VOR). However, there is a need for normative data about how VOR gain is affected by age and also by head velocity, to allow the response of any particular patient to be compared to the responses of healthy subjects in their age range. In this study, we determined for all six semicircular canals, normative values of VOR gain, for each canal across a range of head velocities, for healthy subjects in each decade of life. The VOR gain was measured for all canals across a range of head velocities for at least 10 healthy subjects in decade age bands: 10–19, 20–29, 30–39, 40–49, 50–59, 60–69, 70–79, 80–89. The compensatory eye movement response to a small, unpredictable, abrupt head rotation (head impulse) was measured by the ICS impulse prototype system. The same operator delivered every impulse to every subject. Vestibulo-ocular reflex gain decreased at high head velocities, but was largely unaffected by age into the 80- to 89-year age group. There were some small but systematic differences between the two directions of head rotation, which appear to be largely due to the fact that in this study only the right eye was measured. The results are considered in relation to recent evidence about the effect of age on VOR performance. These normative values allow the results of any particular patient to be compared to the values of healthy people in their age range and so allow, for example, detection of whether a patient has a bilateral vestibular loss. VOR gain, as measured directly by the eye movement response to head rotation, seems largely unaffected by aging.
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影响因子：
3.4
作者：
McGarvie LA;Martinez-Lopez M;Burgess AM;MacDougall HG;Curthoys IS
通讯作者：
Curthoys IS
DOI：
10.3233/ves-2011-0421
发表时间：
2011-01-01
影响因子：
2.3
作者：
Migliaccio, Americo A.;Cremer, Phillip D.
通讯作者：
Cremer, Phillip D.
影响因子：
9.9
作者：
MacDougall, H. G.;Weber, K. P.;Curthoys, I. S.
通讯作者：
Curthoys, I. S.
影响因子：
2.5
作者：
ROBINSON, DA
通讯作者：
ROBINSON, DA
影响因子：
2.5
作者：
SHIMAZU, H;PRECHT, W
通讯作者：
PRECHT, W