Stromal-dependent tumor promotion by MIF family members.
Stromal-dependent tumor promotion by MIF family members.
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DOI:
10.1016/j.cellsig.2014.09.012
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发表时间:
2014-12
影响因子:
4.8
通讯作者:
Yaddanapudi K
中科院分区:
文献类型:
--
作者:
Mitchell RA;Yaddanapudi K
Solid tumors are composed of a heterogeneous population of cells that interact with each other and with soluble and insoluble factors that, when combined, strongly influence the relative proliferation, differentiation, motility, matrix remodeling, metabolism and microvessel density of malignant lesions. One family of soluble factors that is becoming increasingly associated with pro-tumoral phenotypes within tumor microenvironments is that of the migration inhibitory factor family which includes its namesake, MIF, and its only known family member, D-dopachrome tautomerase (D-DT). This review seeks to highlight our current understanding of the relative contributions of a variety of immune and non-immune tumor stromal cell populations and, within those contexts, will summarize the literature associated with MIF and/or D-DT.
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DOI:
10.1158/1078-0432.ccr-08-1283
发表时间:
2009-02-01
期刊:
Clinical cancer research : an official journal of the American Association for Cancer Research
影响因子:
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作者:
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West RB
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Gabrilovich, DI
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20.3
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DOI:
10.1073/pnas.93.15.7849
发表时间:
1996-07-23
影响因子:
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Bacher, M;Metz, CN;Bucala, R
通讯作者:
Bucala, R