Insights into adenovirus host cell interactions from structural studies.

Insights into adenovirus host cell interactions from structural studies.
复制标题

DOI:
10.1016/j.virol.2008.10.016
复制
发表时间:
2009-02-20
期刊:
影响因子:
3.7
通讯作者:
Stewart, P. L.
Stewart, P. L.
中科院分区:
医学3区
文献类型:
--
作者:
Nemerow, G. R.;Pache, L.;Reddy, V.;Stewart, P. L.

文献摘要

参考文献

被引文献

相似文献

人类腺病毒引起大量急性呼吸道、肠道和眼部感染,但它们也作为揭示细胞和分子生物学基本方面的有用模型系统。此外,复制缺陷型腺病毒正被用于基因转移和疫苗临床试验。在过去的十年中,结构生物学技术的稳步发展有助于揭示腺病毒生命周期中最早的事件以及病毒与宿主免疫系统成分的相互作用的重要见解。这篇综述强调了继续使用基于结构的方法来揭示腺病毒-宿主相互作用的分子特征。
Human adenoviruses cause a significant number of acute respiratory, enteric and ocular infections, however they have also served as useful model systems for uncovering fundamental aspects of cell and molecular biology. In addition, replication-defective forms of adenovirus are being used in gene transfer and vaccine clinical trials. Over the past decade, steady advances in structural biology techniques have helped reveal important insights into the earliest events in the adenovirus life cycle as well as virus interactions with components of the host immune system. This review highlights the continuing use of structure-based approaches to uncover the molecular features of adenovirus—host interactions.
DOI: 10.1038/nm952
发表时间: 2003-11-01
期刊: NATURE MEDICINE
影响因子: 82.9
作者:
Gaggar, A;Shayakhmetov, DM;Lieber, A
通讯作者: Lieber, A
DOI: 10.1038/sj.emboj.7600653
发表时间: 2005-05-04
期刊: EMBO JOURNAL
影响因子: 11.4
作者:
Fabry, CMS;Rosa-Calatrava, M;Schoehn, G
通讯作者: Schoehn, G
DOI: 10.1016/0092-8674(77)90180-5
发表时间: 1977-01-01
期刊: CELL
影响因子: 64.5
作者:
CHOW, LT;GELINAS, RE;ROBERTS, RJ
通讯作者: ROBERTS, RJ
DOI: 10.1128/jvi.68.9.5925-5932.1994
发表时间: 1994-09-01
影响因子: 5.4
作者:
BAI, M;CAMPISI, L;FREIMUTH, P
通讯作者: FREIMUTH, P
DOI: 10.1128/jvi.73.8.6759-6768.1999
发表时间: 1999-08-01
影响因子: 5.4
作者:
Chiu, CY;Mathias, P;Stewart, PL
通讯作者: Stewart, PL