A metastatic invasive mole arising from iatrogenic uterus perforation.
A metastatic invasive mole arising from iatrogenic uterus perforation.
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医源性子宫穿孔引起的转移性侵袭性葡萄胎
DOI：
10.1186/s12885-017-3904-2
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发表时间：
2017-12-20
期刊：
影响因子：
3.8
通讯作者：
Xie X
中科院分区：
文献类型：
--
作者：
Shen Y;Wan X;Xie X
侵蚀性葡萄胎起源于葡萄胎，但其发病机制尚不清楚。医源性子宫穿孔所引起之侵蚀性葡萄胎尚未有报告。1例育龄妇女，因误诊为难免流产，行吸引术后出现剧烈腹痛、急性腹腔内出血入院。患者接受了宫腔镜和腹腔镜检查，确认医源性子宫穿孔以及大网膜和盆腔腹膜转移。所有病灶均被切除，最后病理诊断为转移性侵蚀性葡萄胎。病人接受术后化疗与甲氨蝶呤，并提出了良好的预后。医源性子宫穿孔引起的侵蚀性葡萄胎，其转移方式不同于一般的侵蚀性葡萄胎。在对葡萄胎妊娠行吸引术时应注意预防子宫穿孔。
Invasive mole derives from hydatidiform mole, but its pathogenesis remains unknown. Invasive mole arising from iatrogenic uterine perforation has not been reported yet. A reproductive woman was admitted because she suffered form severe abdominal pain and acute intra-abdominal hemorrhage after suction evacuation due to misdiagnosis as inevitable abortion. The patient underwent hysteroscopy and laparoscopy, by which an iatrogenic uterine perforation and omentum and pelvic peritoneum metastases were confirmed. All lesions were removed and the final pathological diagnosis was metastatic invasive mole. The patient underwent post-operative chemotherapy with methotrexate and presented a good prognosis. Invasive mole arising form iatrogenic uterine perforation displays an unusual metastatic manner other than general invasive moles. The prevention of uterine perforation should be emphasized during suction evacuation for mole pregnancy.
影响因子：
50.5
作者：
Seckl, M. J.;Sebire, N. J.;Sessa, C.
通讯作者：
Sessa, C.
影响因子：
168.9
作者：
Seckl, Michael J.;Sebire, Neil J.;Berkowitz, Ross S.
通讯作者：
Berkowitz, Ross S.