Development of a 4-Layer DOI TOF-PET detector module with a 6 mm-pitch MPPC array
Development of a 4-Layer DOI TOF-PET detector module with a 6 mm-pitch MPPC array
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开发具有 6 毫米间距 MPPC 阵列的 4 层 DOI TOF-PET 探测器模块
DOI：
10.1109/nssmic.2018.8824383
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Yamaya Taiga
中科院分区：
文献类型：
--
作者：
Takyu Sodai;Yoshida Eiji;Nishikido Fumihiko;Nitta Munetaka;Akamatsu Go;Yamaya Taiga
具有飞行时间（TOF）和相互作用深度（DOI）能力的PET探测器是理想的，但DOI-TOF PET探测器尚未得到很好的研究。在本文中，我们开发了一个4层DOI TOF探测器。关键项目是最近商业化的多像素光子计数器（MPPC）模块（C13500系列，Hamamatsu Photonics K. K.，日本）。MPPC阵列是硅通孔（TSV）类型，其有效面积为6 x 6 mm 3（0.075 mm间距子像素），其被布置为8 x 8阵列。首先，在每个MPPC通道的中心放置一对尺寸为4 × 4 × 10 mm 3的硅酸镥细晶体（LFS）。CRT值为252 ps。之后，其中一个检测器被用作参考检测器。然后，基于我们特殊的反射器布置，将尺寸为2.8 × 2.8 × 5 mm 3的铈掺杂硅酸钇镥（LYSO）晶体布置成8 × 8 × 4层。4层LYSO阵列通过光导耦合到MPPC模块。在4层LYSO晶体块的位置图中，大部分晶体可以被识别。参考探测器位置图中中心部分晶体的平均CRT值为486 ± 106 ps。在第三层和第四层的时间谱中，观察到了其他成分。推测这是由于不完整的晶体鉴定造成的污染。需要校准每个MPPC通道的个体特异性，以进行完整的晶体鉴定。总之，我们开发了一个4层DOI TOF探测器，并获得了约500 ps的参考探测器的平均CRT值。
PET detectors with both time-of-flight (TOF) and depth-of-interaction (DOI) capabilities are ideal, but DOI-TOF PET detectors have not been studied well. In this paper, we develop a 4-layer DOI TOF detector. The key item is a recently commercialized module of multi pixel photon counters (MPPCs) (C13500 series, Hamamatsu Photonics K. K., Japan). The MPPC array is the through silicon via (TSV) type with an effective area of 6 x 6 mm3(0.075 mm pitch sub pixels), which is arranged as an 8 x 8 array. At first, a pair of lutetium fine silicate (LFS) crystals each sized in 4 x 4 x 10 mm3was placed on the center of each one MPPC channel. The CRT value was 252 ps. Afterward one of those detectors was used as the reference detector. Then cerium doped lutetium yttrium orthosilicate (LYSO) crystals sized in 2.8 x 2.8 x 5 mm3were arranged in 8 x 8 x 4-layer based on our special reflector arrangement. The 4-layer LYSO array were coupled to the MPPC modules via a light guide. In the position map of the 4-layer LYSO crystal block, most of crystals could be identified. The averaged CRT value for crystals of the central part in the position map for the reference detector was 486 ± 106 ps. In timing spectrum of the third layer and the fourth layer, other components were observed. This was presumed to be due to contamination caused by incomplete crystal identification. Individual specificity for each MPPC channel was required to be calibrated for complete crystal identification. In conclusion, we developed a 4-layer DOI TOF detector and obtained around 500 ps averaged CRT value for the reference detector.
影响因子：
1.8
作者：
Tsuda, T;Murayama, H;Orita, N
通讯作者：
Orita, N