Optimal performance in a countermanding saccade task.
Optimal performance in a countermanding saccade task.
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DOI:
10.1016/j.brainres.2009.12.018
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发表时间:
2010-03-08
期刊:
影响因子:
2.9
通讯作者:
Cohen, Jonathan D.
中科院分区:
文献类型:
--
作者:
Wong-Lin, KongFatt;Eckhoff, Philip;Holmes, Philip;Cohen, Jonathan D.
关键词:
Countermanding an action is a fundamental form of cognitive control. In a saccade-countermanding task, subjects are instructed that, if a stop signal appears shortly after a target, they are to maintain fixation rather than to make a saccade to the target. In recent years, recordings in the frontal eye fields and superior colliculus of behaving non-human primates have found correlates of such countermanding behavior in movement and fixation neurons. In this work, we extend a previous neural network model of countermanding to account for the high pre-target activity of fixation neurons. We propose that this activity reflects the functioning of control mechanisms responsible for optimizing performance. We demonstrate, using computer simulations and mathematical analysis, that pre-target fixation neuronal activity supports countermanding behavior that maximizes reward rate as a function of the stop signal delay, fraction of stop signal trials, intertrial interval, duration of timeout, and relative reward value. We propose experiments to test these predictions regarding optimal behavior.
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DOI:
10.1126/science.1166112
发表时间:
2009-02-13
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Hafed ZM;Goffart L;Krauzlis RJ
通讯作者:
Krauzlis RJ
影响因子:
2.5
作者:
Hanes, DP;Patterson, WF;Schall, JD
通讯作者:
Schall, JD
影响因子:
16.2
作者:
HESTRIN, S;SAH, P;NICOLL, RA
通讯作者:
NICOLL, RA
影响因子:
5.3
作者:
Heinzle, Jakob;Hepp, Klaus;Martin, Kevan A. C.
通讯作者:
Martin, Kevan A. C.
影响因子:
7.8
作者:
Cutsuridis, Vassilis;Smyrnis, Nikolaos;Perantonis, Stavros
通讯作者:
Perantonis, Stavros