A neural mechanism for microsaccade generation in the primate superior colliculus.

A neural mechanism for microsaccade generation in the primate superior colliculus.
复制标题

DOI:
10.1126/science.1166112
复制
发表时间:
2009-02-13
期刊:
Science (New York, N.Y.)
影响因子:
--
通讯作者:
Krauzlis RJ
Krauzlis RJ
中科院分区:
其他
文献类型:
--
作者:
Hafed ZM;Goffart L;Krauzlis RJ

文献摘要

参考文献

被引文献

相似文献

在注视期间,眼睛不是静止的,而是经常表现出微扫视运动。微扫视的功能是有争议的,主要是因为负责其产生的神经机制是未知的。在这里,我们表明,上级丘(SC),视网膜定位组织结构参与非对称性眼跳目标选择,在微眼跳产生中起着因果作用。SC中央凹部分的神经元在微扫视之前和期间增加其活动,其大小仅为几分钟的弧,并且表现出对这些运动的方向和幅度的选择性。这些神经元的可逆失活显著降低了微扫视率,而不会影响注视。这些结果,再加上SC活动的计算机建模,表明微跳视是由SC控制,并解释了微跳视和视觉注意力之间的联系。
During fixation, the eyes are not still, but often exhibit microsaccadic movements. The function of microsaccades is controversial, largely because the neural mechanisms responsible for their generation are unknown. Here we show that the superior colliculus (SC), a retinotopically organized structure involved in voluntary-saccade target selection, plays a causal role in microsaccade generation. Neurons in the foveal portion of the SC increase their activity before and during microsaccades with sizes of only a few minutes of arc, and exhibit selectivity for the direction and amplitude of these movements. Reversible inactivation of these neurons significantly reduces microsaccade rate without otherwise compromising fixation. These results, coupled with computational modeling of SC activity, demonstrate that microsaccades are controlled by the SC, and explain the link between microsaccades and visual attention.
DOI: 10.1523/jneurosci.1317-08.2008
发表时间: 2008-08-06
影响因子: 5.3
作者:
Hafed, Ziad M.;Goffart, Laurent;Krauzlis, Richard J.
通讯作者: Krauzlis, Richard J.
DOI: 10.1017/s0952523801182118
发表时间: 2001-03-01
影响因子: 1.9
作者:
Snodderly, DM;Kagan, I;Gur, M
通讯作者: Gur, M
DOI: 10.3758/bf03206795
发表时间: 1995-08-01
期刊: PERCEPTION & PSYCHOPHYSICS
影响因子: --
作者:
KINGSTONE, A;FENDRICH, R;REUTERLORENZ, PA
通讯作者: REUTERLORENZ, PA
DOI: 10.1364/josa.46.000987
发表时间: 1956-01-01
影响因子: --
作者:
CORNSWEET, TN
通讯作者: CORNSWEET, TN
DOI: 10.1113/jphysiol.1952.sp004706
发表时间: 1952-01-01
影响因子: 5.5
作者:
BARLOW, HB
通讯作者: BARLOW, HB