The BioGRID Interaction Database: 2008 update.

The BioGRID Interaction Database: 2008 update.
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DOI:
10.1093/nar/gkm1001
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发表时间:
2008-01
影响因子:
14.9
通讯作者:
Tyers M
Tyers M
中科院分区:
生物学2区
文献类型:
--
作者:
Breitkreutz BJ;Stark C;Reguly T;Boucher L;Breitkreutz A;Livstone M;Oughtred R;Lackner DH;Bähler J;Wood V;Dolinski K;Tyers M

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相互作用数据集(Biogrid)数据库(http://www.thebiogrid.org)的生物通用存储库是从主要模型生物体中容纳和分发蛋白质和遗传相互作用的收集的。 BioGrid目前包含来自六种不同物种的198 000多个相互作用,这是从高通量研究和常规集中研究中得出的。通过全面的策划工作,Biogrid现在包括迄今为止在主要文献中报道的几乎完整的相互作用,用于酿酒酵母的萌芽酵母菌和裂变酵母菌schizosaccharomyces pombe。 BioGrid中添加了许多新功能,包括改进的用户界面,以根据不同属性,镜像站点和专用的交互管理系统来显示交互,以在不同位置进行策划。 Biogrid提供了相互作用数据,并每月更新葡萄糖基因组数据库,Flybase和Entrez基因。现在,无限制地可以免费获得生物网络和链接的鱼鹰网络可视化系统的源代码。
The Biological General Repository for Interaction Datasets (BioGRID) database (http://www.thebiogrid.org) was developed to house and distribute collections of protein and genetic interactions from major model organism species. BioGRID currently contains over 198 000 interactions from six different species, as derived from both high-throughput studies and conventional focused studies. Through comprehensive curation efforts, BioGRID now includes a virtually complete set of interactions reported to date in the primary literature for both the budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe. A number of new features have been added to the BioGRID including an improved user interface to display interactions based on different attributes, a mirror site and a dedicated interaction management system to coordinate curation across different locations. The BioGRID provides interaction data with monthly updates to Saccharomyces Genome Database, Flybase and Entrez Gene. Source code for the BioGRID and the linked Osprey network visualization system is now freely available without restriction.
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