Burden and risk factors of mental and substance use disorders among adolescents and young adults in Kenya: results from the Global Burden of Disease Study 2019.
Burden and risk factors of mental and substance use disorders among adolescents and young adults in Kenya: results from the Global Burden of Disease Study 2019.
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DOI：
10.1016/j.eclinm.2023.102328
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发表时间：
2024-01
影响因子：
15.1
通讯作者：
Weaver, Marcia R.
中科院分区：
文献类型：
--
作者：
Kumar, Manasi;Njuguna, Simon;Amin, Nabila;Kanana, Sarah;Tele, Albert;Karanja, Mercy;Omar, Nasri;Yator, Obadia;Wambugu, Christine;Bukusi, David;Weaver, Marcia R.
精神和物质使用障碍是全球主要的公共卫生问题，与之相关的残疾率、发病率和死亡率很高。在肯尼亚等低收入和中等收入国家，心理健康往往不被重视，用于预防和治疗精神和药物滥用障碍的资源也有限。青春期和成年早期是精神和物质使用障碍发展的关键时期，许多疾病都是在这个时期出现的。在肯尼亚，青少年和年轻人精神和药物滥用障碍的负担和风险因素尚不清楚。本研究使用的数据来自 2019 年全球疾病负担 (GBD) 研究。我们从 GBD 结果工具中选择了肯尼亚青少年和年轻人精神和药物使用障碍数量的数据。数据是按心理健康（MH）状况、年龄组和性别提取的。我们使用描述性统计方法来总结和呈现数据。具体来说，我们按年龄组和性别计算了伤残调整生命年（DALY）率、精神和物质使用障碍的危险因素。 2019年，在肯尼亚10-24岁的青少年中，精神障碍是仅次于意外伤害的第二大致残原因，占248,936人[95%不确定区间为175,033； 341,680] DALY，占 2,656,546 DALY 总数的 9.4%。药物滥用障碍占 15,022 [9948; 20,710]伤残调整生命年。精神障碍DALY中以抑郁、焦虑和品行障碍为主，分别占全部DALY的3.1%、2.3%和1.7%。 10-24 岁青少年伤残调整生命年 (DALY) 事件的主要风险因素是欺凌和受害 (66.5%)。儿童期性虐待占 DALY 的 13.7%，铅暴露占 DALY 的 8.5%，亲密伴侣暴力占 DALY 的 11.3% (2%)，所有受害者均为女性，非法药物使用占 DALY 的 (52.7%)。需要在国家和县级加强对心理健康和药物使用负担的监测。迫切需要重点关注年轻男孩的特发性发育性智力障碍、品行障碍和物质使用障碍以及年轻女孩和妇女的抑郁、焦虑和饮食失调的及时筛查和干预。 MK 由 / K43 TW 010716 和 R33MH124149-03 资助。该出版物是在盖茨基金会的资助下得以实现的。
Mental and substance use disorders are a major public health concern globally, with high rates of disability, morbidity, and mortality associated with these. In low- and middle-income countries, such as Kenya, mental health is often given low priority, and resources for the prevention and treatment of mental and substance use disorders are limited. Adolescence and young adulthood are critical periods for the development of mental and substance use disorders, with many disorders emerging during this time. In Kenya, the burden and risk factors of mental and substance use disorders among adolescents and young adults is not well understood. The data used in this study were obtained from the Global Burden of Disease (GBD) Study 2019. We selected the data on the number of mental and substance use disorders among adolescents and young adults in Kenya from the GBD results tool. The data were extracted by mental health (MH) condition, by age group and by sex. We used descriptive statistical methods to summarise and present the data. Specifically, we calculated the disability-adjusted life-years (DALYs) rates, risk factors of mental and substance use disorders by age group and sex. In 2019, among 10–24-year-olds in Kenya, mental disorders ranked as the second leading cause of disability, following unintentional injuries, and accounted for 248,936 [95% uncertainty interval 175,033; 341,680] DALYs or 9.4% of 2,656,546 total DALYs. Substance use disorders accounted 15,022 [9948; 20,710] DALYs. Depressive, anxiety, and conduct disorders accounted for the most DALYs of mental disorders accounting for 3.1%, 2.3% and 1.7% of the total DALYs, respectively. The main risk factors for incident DALYs in 10–24-year-olds were bullying and victimization (66.5%). Childhood sexual abuse accounted for 13.7% of the DALYs, lead exposure accounted for 8.5% of the DALYs, intimate partner violence accounted for 11.3% of the DALYs (2%) with all victims being females, and illicit drug use accounted for (52.7%) of DALYs. Improved surveillance of mental health and substance use burden at national and county levels is needed. Focus on timely screening and intervention for idiopathic developmental intellectual disability, conduct disorder, and substance use disorder in young boys and depression, anxiety, and eating disorders in young girls and women is critically needed. MK is funded by / K43 TW 010716 and R33MH124149-03. The publication was made possible by funding from the Gates Foundation.
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影响因子：
3.7
作者：
Jörns-Presentati A;Napp AK;Dessauvagie AS;Stein DJ;Jonker D;Breet E;Charles W;Swart RL;Lahti M;Suliman S;Jansen R;van den Heuvel LL;Seedat S;Groen G
通讯作者：
Groen G
影响因子：
4.4
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影响因子：
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作者：
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通讯作者：
Ndetei, David M.
在肯尼亚建模和映射疾病负担。
影响因子：
4.6
作者：
Frings M;Lakes T;Müller D;Khan MMH;Epprecht M;Kipruto S;Galea S;Gruebner O
通讯作者：
Gruebner O
影响因子：
168.9
作者：
Micah, Angela E.;Su, Yanfang;Dieleman, Joseph L.
通讯作者：
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