Salmon provides fast and bias-aware quantification of transcript expression.
Salmon provides fast and bias-aware quantification of transcript expression.
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DOI:
10.1038/nmeth.4197
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发表时间:
2017-04
期刊:
影响因子:
48
通讯作者:
Kingsford C
中科院分区:
文献类型:
--
作者:
Patro R;Duggal G;Love MI;Irizarry RA;Kingsford C
We introduce Salmon, a method for quantifying transcript abundance from RNA-seq reads that is accurate and fast. Salmon is the first transcriptome-wide quantifier to correct for fragment GC content bias, which we demonstrate substantially improves the accuracy of abundance estimates and the reliability of subsequent differential expression analysis. Salmon combines a new dual-phase parallel inference algorithm and feature-rich bias models with an ultra-fast read mapping procedure.
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影响因子:
46.9
作者:
Patro, Rob;Mount, Stephen M.;Kingsford, Carl
通讯作者:
Kingsford, Carl
影响因子:
64.8
作者:
通讯作者:
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影响因子:
48
作者:
Langmead, Ben;Salzberg, Steven L.
通讯作者:
Salzberg, Steven L.
影响因子:
7
作者:
Li JJ;Huang H;Bickel PJ;Brenner SE
通讯作者:
Brenner SE
DOI:
10.1093/bioinformatics/btv483
发表时间:
2015-12-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Hensman J;Papastamoulis P;Glaus P;Honkela A;Rattray M
通讯作者:
Rattray M