Association between patient-reported hearing and visual impairments and functional, psychological, and cognitive status among older adults with cancer.
Association between patient-reported hearing and visual impairments and functional, psychological, and cognitive status among older adults with cancer.
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DOI：
10.1002/cncr.31540
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发表时间：
2018-08-01
期刊：
影响因子：
6.2
通讯作者：
Hurria A
中科院分区：
文献类型：
--
作者：
Soto-Perez-de-Celis E;Sun CL;Tew WP;Mohile SG;Gajra A;Klepin HD;Owusu C;Gross CP;Muss HB;Lichtman SM;Chapman AE;Cohen HJ;Dale W;Kim H;Fernandes S;Katheria V;Hurria A
听力和视力障碍在社区居住的老年人中很常见，并且与心理、功能和认知缺陷有关。然而，人们对老年癌症患者中它们的患病率知之甚少。这是一项二级分析，结合了两个65岁以上的实体瘤患者接受化疗的前瞻性队列。我们评估了患者报告的听力和/或视力障碍（定义为自我报告的一般/差级）与身体功能、日常生活工具活动（IADLs）、焦虑、抑郁和认知之间的关系。描述性分析总结患者及治疗特点。采用单因素方差分析和卡方检验来检查有无感觉障碍患者之间的差异。运用逻辑回归分析感觉障碍与预后之间的关系。在750例实体瘤患者（中位年龄72岁）中（29%为乳腺/妇科，28%为肺部，27%为胃肠道），18%仅报告听力障碍；11%的人仅报告有视力障碍；7%的人有双重感觉障碍。听力障碍与IADL依赖（OR 2.0）、抑郁（OR 1.7）和焦虑（OR 1.6）相关。视觉障碍与IADL依赖（OR 2.0）、身体功能差（OR 1.9）和抑郁（OR 2.7）相关。双重损害与IADL依赖（OR 2.8）、焦虑（OR 2.3）、抑郁（OR 2.6）和认知障碍（OR 3.3）相关。感觉障碍在老年癌症患者中很常见。感觉障碍患者更有可能出现功能、心理和认知缺陷。应该研究旨在改善老年癌症患者视力和听力的干预措施。
Hearing and visual impairment are common among community-dwelling older adults, and they are associated with psychological, functional, and cognitive deficits. However, little is known about their prevalence among older patients with cancer. This is a secondary analysis combining two prospective cohorts of adults over 65 with solid tumors receiving chemotherapy. We assessed the association between patient-reported hearing and/or visual impairment (defined as fair/poor grading by self-report) and physical function, instrumental activities of daily living (IADLs), anxiety, depression, and cognition. Descriptive analyses were conducted to summarize patient and treatment characteristics. One-way analysis of variance and Chi-square tests as appropriate were conducted to examine differences between patients with and without sensory impairments. Logistic regression was utilized to analyze associations between sensory impairments and outcomes. Among 750 patients (median age 72) with solid tumors (29% breast/gynecological; 28% lung; 27% gastrointestinal), 18% reported hearing impairment alone; 11% reported visual impairment alone; and 7% reported dual sensory impairment. Hearing impairment was associated with IADL dependence (OR 2.0), depression (OR 1.7), and anxiety (OR 1.6). Visual impairment was associated with IADL dependence (OR 2.0), poor physical function (OR 1.9), and depression (OR 2.7). Dual impairment was associated with IADL dependence (OR 2.8), anxiety (OR 2.3), depression (OR 2.6), and cognitive impairment (OR 3.3). Sensory impairment is common among older adults with cancer. Patients with sensory impairment are more likely to have functional, psychological and cognitive deficits. Interventions aimed at improving the vision and hearing of older adults with cancer should be studied.
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影响因子：
6.3
作者：
Pinto JM;Wroblewski KE;Huisingh-Scheetz M;Correia C;Lopez KJ;Chen RC;Kern DW;Schumm PL;Dale W;McClintock MK
通讯作者：
McClintock MK
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Crews, JE;Campbell, VA
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