Prenatal stress and risk of behavioral morbidity from age 2 to 14 years: The influence of the number, type, and timing of stressful life events

Prenatal stress and risk of behavioral morbidity from age 2 to 14 years: The influence of the number, type, and timing of stressful life events
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产前压力和 2 至 14 岁行为发病风险:压力生活事件的数量、类型和时间的影响

DOI:
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发表时间:
2011
影响因子:
3.3
通讯作者:
J. Newnham
J. Newnham
中科院分区:
心理学2区
文献类型:
--
作者:
M. Robinson;E. Mattes;W. Oddy;C. Pennell;Anke van Eekelen;Neil J. McLean;P. Jacoby;Jianghong Li;N. de Klerk;S. Zubrick;F. Stanley;J. Newnham

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摘要母亲在怀孕期间经历的压力事件与后代行为发育的一些不良后果有关,但产前压力的测量和解释在报道的研究中各不相同。Raine研究招募了2900名孕妇,并记录了妊娠沿着和34周时经历的生活压力事件以及大量的社会人口学数据。母亲暴露于生活压力事件的进一步记录时,孩子们进行了随访,结合行为评估,在年龄2,5,8,10和14岁,使用儿童行为检查表。母亲在怀孕期间经历的多重压力事件与后代随后的行为问题有关。独立(例如,亲属死亡、失业)和依赖性压力事件(例如,经济问题、婚姻问题)都与2至14岁之间心理健康发病率的增加显著相关。在怀孕的前18周暴露于压力事件与随后的总发病率和外部发病率在怀孕34周报告的事件显示出类似的关联。这些结果是独立的产后应激暴露。改善对怀孕期间长期承受压力的妇女的支持可能会改善其后代在以后生活中的心理健康。
Abstract The maternal experience of stressful events during pregnancy has been associated with a number of adverse consequences for behavioral development in offspring, but the measurement and interpretation of prenatal stress varies among reported studies. The Raine Study recruited 2900 pregnancies and recorded life stress events experienced by 18 and 34 weeks' gestation along with numerous sociodemographic data. The mother's exposure to life stress events was further documented when the children were followed-up in conjunction with behavioral assessments at ages 2, 5, 8, 10, and 14 years using the Child Behavior Checklist. The maternal experience of multiple stressful events during pregnancy was associated with subsequent behavioral problems for offspring. Independent (e.g., death of a relative, job loss) and dependent stress events (e.g., financial problems, marital problems) were both significantly associated with a greater incidence of mental health morbidity between age 2 and 14 years. Exposure to stressful events in the first 18 weeks of pregnancy showed similar associations with subsequent total and externalizing morbidity to events reported at 34 weeks of gestation. These results were independent of postnatal stress exposure. Improved support for women with chronic stress exposure during pregnancy may improve the mental health of their offspring in later life.
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