Generation of a human-derived induced pluripotent stem cell line (SIAISi012-A) from an 82-year-old healthy Chinese Han male.
Generation of a human-derived induced pluripotent stem cell line (SIAISi012-A) from an 82-year-old healthy Chinese Han male.
复制标题
从 82 岁健康的中国汉族男性中产生人源诱导多能干细胞系 (SIAISi012-A)。
DOI:
10.1016/j.scr.2021.102186
复制
发表时间:
2021-01
影响因子:
1.2
通讯作者:
Ying Wang
中科院分区:
文献类型:
--
作者:
Jinhui Guo;Fang Fang;Qiuting Dai;Wenxin Zhang;Weihao Di;Jiaan Hu;Jian Zhao;Jiumei Cao;Ying Wang
As the global median population age increases, neurological diseases associated with aging pose significant challenges to human health. Appropriate modeling systems can be useful tools to better understand the mechanism of age-related neuronal degeneration diseases. Here, we successfully generated an iPSC-derived modeling system of an 82-year-old healthy man, this newly established line showed that all pluripotent markers were expressed, and the differentiation potential was confirmed by trilineage differentiation. STR profiling proved the cell line identity, and G-binding showed the normal karyotype.
登录
查看更多内容
DOI:
10.1016/s0093-3619(08)70915-8
发表时间:
2008
期刊:
Yearbook of Dermatology and Dermatologic Surgery
影响因子:
--
作者:
B. Thiers
通讯作者:
B. Thiers
影响因子:
64.5
作者:
Takahashi, Kazutoshi;Tanabe, Koji;Yamanaka, Shinya
通讯作者:
Yamanaka, Shinya
影响因子:
5.7
作者:
Itskovitz-Eldor, J;Schuldiner, M;Benvenisty, N
通讯作者:
Benvenisty, N
影响因子:
48
作者:
Okita, Keisuke;Matsumura, Yasuko;Yamanaka, Shinya
通讯作者:
Yamanaka, Shinya