Tensile properties of commonly used prolapse meshes.
Tensile properties of commonly used prolapse meshes.
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DOI：
10.1007/s00192-008-0781-x
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发表时间：
2009-07
影响因子：
1.8
通讯作者：
Moalli, Pamela A.
中科院分区：
文献类型：
--
作者：
Jones, Keisha A.;Feola, Andrew;Meyn, Leslie;Abramowitch, Steven D.;Moalli, Pamela A.
尽管目前可用的大多数合成补片都是轻质大孔聚丙烯补片，但它们在孔径、编织图案和表面特征方面存在差异，所有这些都可能影响性能。在本研究中，我们使用拉伸试验方案比较了4种常用脱垂补片相对于Gynecare PS ™的生物力学性能。将全长补片[Gynecare PS™（Ethicon）、Pelvitex ™（Bard）、Popmesh™、Timesh ™（Caldera）和Polyform（Boston Scientific）]分成15 × 5 cm样本。使用光学显微镜来确定孔径。对于拉伸试验，对每个补片加载至失效（每组n=5）或循环加载（每组n=3）。从大部分双线性载荷-伸长率曲线中提取的数据包括低刚度和高刚度、它们之间的过渡点（拐点）、失效载荷和相对伸长率。显微镜分析表明，所有补片的孔径均不同。除Popmesh显示线性行为外，所有脱垂补片的特征均为初始刚度非常低，在高刚度区域增加一个数量级。较新的补片硬度比Gynecare低70%-90%（p< 0.05），并且更容易在循环载荷下变形（更大的永久伸长率; p < 0.001）。补片重量与失效载荷之间存在显著正相关性（p< 0.001）。较新的补片硬度明显低于Gynecare PS。这些补片的显著永久性伸长可能是重要的考虑因素，特别是在术后早期，此时组织尚未生长。
Although most currently available synthetic meshes are lightweight, macroporous polypropylene, they differ in regard to pore size, knit pattern and surface characteristics, all of which may impact behavior. In this study, we compare the biomechanical properties of 4 commonly used prolapse meshes relative to Gynecare PS ™, using a tensile testing protocol. Full length meshes [Gynecare PS™ (Ethicon), Pelvitex ™ (Bard), Popmesh™, Timesh ™ (Caldera), and Polyform (Boston Scientific)] were divided into 15 × 5 cm samples. Light microscopy was used to define pore size. For tensile testing, each mesh was either loaded to failure (n=5 per group) or cyclically loaded (n=3 per group). Data abstracted from the largely bilinear load-elongation curves included the low and high stiffness, the point of transition between them (inflection point), the load at failure, and the relative elongation. Microscopic analysis demonstrated that the pore size for all of the meshes were distinct. With the exception of Popmesh which displayed linear behavior, all prolapse meshes were characterized by a very low initial stiffness increasing by an order of magnitude into the high stiffness region. The newer meshes were 70%-90% less stiff than Gynecare (p< 0.05) and more readily deformed in response to cyclical loading (greater permanent elongation; p < 0.001). There was a significant positive correlation between mesh weight and load at failure, (p< 0.001). Newer meshes are significantly less stiff than Gynecare PS. The significant amount of permanent elongation of these meshes may be important to consider, especially during the early post-operative period when tissue in growth has yet to take place.
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影响因子：
9.6
作者：
Jones, NHJR;Healy, JC;Allen-Mersh, TG
通讯作者：
Allen-Mersh, TG
影响因子：
1.5
作者：
Fenner, DE
通讯作者：
Fenner, DE
影响因子：
1.8
作者：
Cosson, M;Debodinance, P;Ego, A
通讯作者：
Ego, A
影响因子：
7.2
作者：
Olsen, AL;Smith, VJ;Clark, AL
通讯作者：
Clark, AL
DOI：
10.1007/bf01901604
发表时间：
1998-01-01
期刊：
International urogynecology journal and pelvic floor dysfunction
影响因子：
--
作者：
Flood, C G;Drutz, H P;Waja, L
通讯作者：
Waja, L