Weight suppression as a predictor of weight gain and response to intensive behavioral treatment in patients with anorexia nervosa.
Weight suppression as a predictor of weight gain and response to intensive behavioral treatment in patients with anorexia nervosa.
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DOI：
10.1016/j.brat.2012.02.006
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发表时间：
2012-04
影响因子：
4.1
通讯作者：
Marcus MD
中科院分区：
文献类型：
--
作者：
Wildes JE;Marcus MD
以前的研究已经证明，体重抑制（一个人的最高成人体重减去当前体重）预测在治疗贪食症谱系障碍期间体重增加和饮食失调症状，但没有研究检查神经性厌食症（AN）患者的体重抑制。因此，本研究试图在大样本AN患者（N = 185）中描述体重抑制的特征，并评估入院时接受强化行为治疗的体重抑制是否可预测出院时的体重增加和临床结局。AN患者的体重抑制范围为0 kg至78 kg（M [SD] = 17.1 [10.8] kg）。即使在控制了入院时的体重指数、接受强化治疗的时间和类型、限制与暴饮暴食/清除AN亚型以及研究结果的其他预测因素后，体重抑制水平越高，在强化治疗期间预测总体重增加越多、体重增加速度越快和暴食症状。这些发现与先前的研究一致，这些研究记录了体重抑制在治疗进食障碍中的临床意义。未来的工作需要复制目前的研究结果，并检查体重抑制是否可以预测强化治疗后AN的病程。
Previous studies have documented that weight suppression (a person’s highest adult weight minus current weight) predicts weight gain and disordered eating symptoms during treatment of bulimia spectrum disorders, but no research has examined weight suppression in individuals with anorexia nervosa (AN). Thus, this study sought to characterize weight suppression in a large sample of patients with AN (N = 185), and to evaluate whether weight suppression at admission for intensive behavioral treatment predicts weight gain and clinical outcomes at discharge. Weight suppression varied from 0 kg to78 kg (M [SD] = 17.1 [10.8] kg) in AN patients. Higher levels of weight suppression predicted greater total weight gain, a faster rate of weight gain, and bulimic symptoms during intensive treatment even after controlling for body mass index on admission, length and type of intensive treatment received, restricting versus binge-eating/purging AN subtype, and other predictors of study outcomes. These findings converge with previous research documenting the clinical significance of weight suppression in the treatment of eating disorders. Future work is needed to replicate the current findings, and examine whether weight suppression predicts the course of AN following discharge from intensive treatment.
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