Induction of classical transplantation tolerance in the adult
Induction of classical transplantation tolerance in the adult
复制标题
成人经典移植耐受的诱导
DOI：
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发表时间：
1989
影响因子：
15.3
通讯作者：
H. Waldmann
中科院分区：
文献类型：
--
作者：
S. Qin;S. Cobbold;Richard Benjamin;H. Waldmann
Transplantation tolerance across histoincompatibilities in multiple non- H-2 minors (B10.BR into CBA/Ca) and "minor" plus H-2D (B10.A into CBA/Ca) antigens has been achieved successfully by combined adult bone marrow transplantation and treatment with CD4 and CD8 mAbs. The tolerant state was confirmed by permanent acceptance of donor strain skin grafts, and in vitro unresponsiveness to donor cells. Tolerance was associated with partial donor chimerism to various degrees. Tolerance to minor transplantation antigens induced in this manner was restricted to recipient-type MHC. The possibility was raised that tolerance resulted, at least in part, from clonal anergy rather than deletion.
小鼠模型系统中骨髓移植排斥的机制。
影响因子：
0.9
作者：
Dennert,G;Knobloch,C;Yankelevich,B
通讯作者：
Yankelevich,B
移植后给予抗淋巴细胞血清或抗淋巴细胞血清加骨髓处理的植皮小鼠外周血淋巴细胞的影响。
影响因子：
6.2
作者：
DeFazio,SR;Hartner,WC;Monaco,AP;Gozzo,JJ
通讯作者：
Gozzo,JJ