Pre-surgical CT-assessment of neurogenic myositis ossificans of the hip and risk factors of recurrence: a series of 101 consecutive patients.
Pre-surgical CT-assessment of neurogenic myositis ossificans of the hip and risk factors of recurrence: a series of 101 consecutive patients.
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DOI：
10.1186/s12891-016-1294-2
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发表时间：
2016-10-18
影响因子：
2.3
通讯作者：
Carlier RY
中科院分区：
文献类型：
--
作者：
Law-Ye B;Hangard C;Felter A;Safa D;Denormandie P;Genet F;Carlier RY
神经源性骨化性肌炎是一种罕见的致残性病变，其特征是严重的外周或中枢神经系统损伤后关节周围异位骨化。它导致关节强直和血管或神经压迫。我们的研究旨在描述术前发现的患者与NMO的髋关节使用双相计算机断层扫描（CT）。在2006年至2012年期间，我们回顾性分析了101例髋关节NMO患者。我们分析了所有的CT和手术报告，按照标准化的网格描述骨瘤及其与关节囊、血管和神经以及骨矿化的关系。我们在随访期间研究了手术并发症和复发。采用卡方检验和Fischer’s检验比较正态分布和非正态分布的定性值。用单因素方差分析（ANOVA）检验分析定量值。术前CT和手术观察结果之间的一致性采用Cohen kappa检验进行评价。术前CT与手术结果之间的相关性在与血管的关系方面非常好（0.82），在与坐骨神经（0.62）和关节囊（0.68）的关系方面良好。关节囊紧密接触或破裂（p = 0.005）、关节间隙狭窄（p = 0.007）和骨脱矿（p < 0.001）与NMO复发相关。双相增强CT允许术前评估NMO，与手术观察结果具有良好的相关性，并有助于预防手术并发症。
Neurogenic Myositis Ossificans (NMO) is a rare disabling pathology characterized by peri-articular heterotopic ossifications following severe peripheral or central nervous system injuries. It results in ankylosis and vessels or nerves compressions. Our study aimed to describe the pre-operative findings of patients with NMO of the hip using biphasic computerized tomography (CT). Between 2006 and 2012, we retrospectively analyzed 101 consecutive patients with hip NMO. We analyzed all CTs and surgical reports following a standardized grid depicting the osteoma and its relations with joint capsule, vessels and nerves and bone mineralization. We studied surgical complications and recurrence during follow-up. Chi2-test and Fischer’s test were performed to compare qualitative values with respectively normal and non-normal distribution. Quantitative values were analyzed with a one factor analysis of variance (ANOVA) test. Agreement between pre-surgical CT and surgical observations was evaluated with Cohen’s kappa test. Correlation between pre-operative CT and surgical findings was excellent regarding relationships with vessels (0,82) and was good concerning relationships with sciatic nerves (0.62) and with joint capsule (0.68). Close contact or disruption of joint capsule (p = 0.005), joint space narrowing (p = 0.007) and bone demineralization (p < 0.001) were correlated with NMO recurrence. Biphasic enhanced-CT allows pre-operative assessment of NMO with good correlation to surgical observations and helps prevent surgical complications.
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DOI：
10.1097/00005373-200006000-00010
发表时间：
2000-06-01
影响因子：
--
作者：
Ebinger, T;Roesch, M;Schulte, M
通讯作者：
Schulte, M
影响因子：
3.6
作者：
Weber, EWG;Slappendel, R;Spruit, M
通讯作者：
Spruit, M
影响因子：
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作者：
Genêt F;Jourdan C;Schnitzler A;Lautridou C;Guillemot D;Judet T;Poiraudeau S;Denormandie P
通讯作者：
Denormandie P
影响因子：
4.2
作者：
Chalidis, Byron;Stengel, Dirk;Giannoudis, Peter V.
通讯作者：
Giannoudis, Peter V.
DOI：
10.1302/0301-620x.87b3.14737
发表时间：
2005-03-01
影响因子：
--
作者：
Carlier, RY;Safa, DML;Vallée, CA
通讯作者：
Vallée, CA