Impact of host age on viral and bacterial communities in a waterbird population.
Impact of host age on viral and bacterial communities in a waterbird population.
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DOI：
10.1038/s41396-022-01334-4
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发表时间：
2023-03
期刊：
影响因子：
11
通讯作者：
Pybus, Oliver G.
中科院分区：
文献类型：
--
作者：
Hill, Sarah C.;Francois, Sarah;Theze, Julien;Smith, Adrian L.;Simmonds, Peter;Perrins, Christopher M.;van der Hoek, Lia;Pybus, Oliver G.
野生动物藏匿着可能危害人类或牲畜健康的病原体，是大多数新出现的传染病的源头。很少考虑野生动物种群年龄结构的变化或年龄分层行为如何改变物种内病原体检测的水平，或溢出到其他物种的风险。健康动物体内的微生物可以成为了解和预测具有更大健康问题的病原体动态的重要模型，这些病原体由于相对罕见而难以在野生种群中进行研究。因此，我们使用了宏基因组学的方法来共同检测从健康的野生鸟类种群（天鹅;疣鼻天鹅）收集的粪便中的病毒和原核携带，该种群已进行了长期研究。使用来自已知个体的223个样本，使我们能够以前所未有的详细程度比较成人和青少年之间原核和真核病毒携带的差异。我们发现并鉴定了77种新的病毒物种，其中21%属于鸟类感染科，并描述了C.颜色。虽然未成年人和成年人之间的微生物群多样性没有差异，但50%（4/8）的鸟类感染病毒家族（小核糖核酸病毒，星状病毒，腺病毒和博尔纳病毒）和3.4%（9/267）的原核生物家族（包括螺旋杆菌科，螺旋体科和黄杆菌科）在未成年人和成年人之间存在差异丰富和/或流行。这表明，影响野生动物种群年龄结构的扰动可能会改变循环动力学和微生物（可能包括病原体）的溢出风险。
Wildlife harbour pathogens that can harm human or livestock health and are the source of most emerging infectious diseases. It is rarely considered how changes in wildlife population age-structures or how age-stratified behaviours might alter the level of pathogen detection within a species, or risk of spillover to other species. Micro-organisms that occur in healthy animals can be an important model for understanding and predicting the dynamics of pathogens of greater health concern, which are hard to study in wild populations due to their relative rarity. We therefore used a metagenomic approach to jointly characterise viral and prokaryotic carriage in faeces collected from a healthy wild bird population (Cygnus olor; mute swan) that has been subject to long-term study. Using 223 samples from known individuals allowed us to compare differences in prokaryotic and eukaryotic viral carriage between adults and juveniles at an unprecedented level of detail. We discovered and characterised 77 novel virus species, of which 21% belong putatively to bird-infecting families, and described the core prokaryotic microbiome of C. olor. Whilst no difference in microbiota diversity was observed between juveniles and adult individuals, 50% (4/8) of bird-infecting virus families (picornaviruses, astroviruses, adenoviruses and bornaviruses) and 3.4% (9/267) of prokaryotic families (including Helicobacteraceae, Spirochaetaceae and Flavobacteriaceae families) were differentially abundant and/or prevalent between juveniles and adults. This indicates that perturbations that affect population age-structures of wildlife could alter circulation dynamics and spillover risk of microbes, potentially including pathogens.
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DOI：
10.3390/ijerph17061998
发表时间：
2020-03-02
影响因子：
--
作者：
Chevalier, Veronique;Marsot, Maud;Beck, Cecile
通讯作者：
Beck, Cecile
影响因子：
3.7
作者：
Frafjord, Karl
通讯作者：
Frafjord, Karl
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y
影响因子：
5.4
作者：
Chong, Rowena;Shi, Mang;Barrs, Vanessa R.
通讯作者：
Barrs, Vanessa R.
影响因子：
2
作者：
Begg, CM;Begg, KS;Mills, MGL
通讯作者：
Mills, MGL