Elevated blood monocyte counts in alcohol-associated hepatitis.

Elevated blood monocyte counts in alcohol-associated hepatitis.
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DOI:
10.1002/jgh3.12707
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发表时间:
2022-03
期刊:
JGH open : an open access journal of gastroenterology and hepatology
影响因子:
--
通讯作者:
Weinman SA
Weinman SA
中科院分区:
其他
文献类型:
--
作者:
Voss JK;Li Z;Weinman SA

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在这项对164例酒精相关性肝炎患者的回顾性研究中,我们发现平均单核细胞绝对计数为0.95千个细胞/L,显著高于正常上限(0.80千个细胞/μL)(P < 0.0001)。单核细胞计数与MELD评分(R = 0.400,P < 0.0001)和Madelman判别函数(R = 0.330,P < 0.0001)测量的疾病严重程度相关。
In this retrospective study of 164 patients with alcohol‐associated hepatitis, we find that the mean absolute monocyte count is 0.95 thousand cells/L, which is significantly higher than the upper limit of normal (0.80 thousand cells/μL) (P < 0.0001). Monocyte count is correlated with disease severity as measured by MELD score (R = 0.400, P < 0.0001) and Maddrey discriminant function (R = 0.330, P < 0.0001).
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