Ethanol Reduces Asymmetry of Visual rCBF Responses

Ethanol Reduces Asymmetry of Visual rCBF Responses
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乙醇减少视觉 rCBF 反应的不对称性

DOI:
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发表时间:
1994
影响因子:
6.3
通讯作者:
D. Ingvar
D. Ingvar
中科院分区:
医学1区
文献类型:
--
作者:
P. E. Wendt;J. Risberg;G. Stenberg;I. Rosén;D. Ingvar

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在 10 名健康男性受试者服用 1 g/kg 体重的乙醇之前和之后测量了视觉区域 CBF (rCBF) 反应。该剂量会引起充分的脑血管舒张。然而,在这两种情况下均发现双侧枕骨显着增大。显然,乙醇作用后神经元活动和 rCBF 之间的耦合得以保留。然而,在清醒状态下,右侧枕叶和后顶叶流量的增加大于左侧。醉酒期间,不对称性消失,可能代表视觉信息的处理更加无差别。我们认为乙醇会减少左后皮质的抑制并减少右半球的信息处理。
Visual regional CBF (rCBF) responses were measured in 10 healthy male subjects before and after an ethanol dose of 1 g/kg body weight. This dose induces well-established cerebral vasodilatation. However, significant bilateral occipital increases were found in both conditions. Apparently, the coupling between neuronal activity and rCBF is preserved following ethanol. The occipital and posterior parietal flow increases were, however, larger on the right than the left side in the sober state. During inebriation the asymmetry disappeared, possibly representing a more undifferentiated processing of visual information. We propose that ethanol causes a reduced inhibition of the left posterior cortex and a reduction of right-hemisphere information processing.
DOI: 10.1126/science.1948051
发表时间: 1991-11-01
期刊: SCIENCE
影响因子: 56.9
作者:
BELLIVEAU, JW;KENNEDY, DN;ROSEN, BR
通讯作者: ROSEN, BR